Christian. Liedtke, et.al., Loss of caspase-8 protects mice against inflammation-related hepatocarcinogenesis but induces non-apoptotic liver injury., Gastroenterology, 2011, 141

http://rdf.ncbi.nlm.nih.gov/pubmed/21878202

Christian. Liedtke, et.al., Loss of caspase-8 protects mice against inflammation-related hepatocarcinogenesis but induces non-apoptotic liver injury., Gastroenterology, 2011, 141

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal circulating enzyme level_Casp8<tm1Clie>/Casp8<tm1Clie>,Ikbkg<tm1.1Chtr>/Ikbkg<tm1.1Chtr>,Tg(Alb1-cre)7Gsc/0
  http://metadb.riken.jp/0001570I129P2OlaHsdC57BL6FVBNCasp8tm1ClieCasp8tm1ClieIkbkgtm11ChtrIkbkgtm11ChtrTgAlb1cre7Gsc0Ikbkgtm11ChtrCasp8tm1ClieTgAlb1cre7Gsc
• abnormal biliary tract morphology_Casp8<tm1Clie>/Casp8<tm1Clie>,Ikbkg<tm1.1Chtr>/Ikbkg<tm1.1Chtr>,Tg(Alb1-cre)7Gsc/0
  http://metadb.riken.jp/0005083I129P2OlaHsdC57BL6FVBNCasp8tm1ClieCasp8tm1ClieIkbkgtm11ChtrIkbkgtm11ChtrTgAlb1cre7Gsc0Ikbkgtm11ChtrCasp8tm1ClieTgAlb1cre7Gsc
• abnormal liver morphology_Casp8<tm1Clie>/Casp8<tm1Clie>,Ikbkg<tm1.1Chtr>/Ikbkg<tm1.1Chtr>,Tg(Alb1-cre)7Gsc/0
  http://metadb.riken.jp/0000598I129P2OlaHsdC57BL6FVBNCasp8tm1ClieCasp8tm1ClieIkbkgtm11ChtrIkbkgtm11ChtrTgAlb1cre7Gsc0Ikbkgtm11ChtrCasp8tm1ClieTgAlb1cre7Gsc
• liver fibrosis_Casp8<tm1Clie>/Casp8<tm1Clie>,Ikbkg<tm1.1Chtr>/Ikbkg<tm1.1Chtr>,Tg(Alb1-cre)7Gsc/0
  http://metadb.riken.jp/0003333I129P2OlaHsdC57BL6FVBNCasp8tm1ClieCasp8tm1ClieIkbkgtm11ChtrIkbkgtm11ChtrTgAlb1cre7Gsc0Ikbkgtm11ChtrCasp8tm1ClieTgAlb1cre7Gsc
• hepatic necrosis_Casp8<tm1Clie>/Casp8<tm1Clie>,Ikbkg<tm1.1Chtr>/Ikbkg<tm1.1Chtr>,Tg(Alb1-cre)7Gsc/0
  http://metadb.riken.jp/0001654I129P2OlaHsdC57BL6FVBNCasp8tm1ClieCasp8tm1ClieIkbkgtm11ChtrIkbkgtm11ChtrTgAlb1cre7Gsc0Ikbkgtm11ChtrCasp8tm1ClieTgAlb1cre7Gsc
• increased susceptibility to injury_Casp8<tm1Clie>/Casp8<tm1Clie>,Tg(Alb1-cre)7Gsc/0
  http://metadb.riken.jp/0005165I129P2OlaHsdC57BL6FVBNCasp8tm1ClieCasp8tm1ClieTgAlb1cre7Gsc0Casp8tm1ClieTgAlb1cre7Gsc
• enlarged liver_Casp8<tm1Clie>/Casp8<tm1Clie>,Ikbkg<tm1.1Chtr>/Ikbkg<tm1.1Chtr>,Tg(Alb1-cre)7Gsc/0
  http://metadb.riken.jp/0000599I129P2OlaHsdC57BL6FVBNCasp8tm1ClieCasp8tm1ClieIkbkgtm11ChtrIkbkgtm11ChtrTgAlb1cre7Gsc0Ikbkgtm11ChtrCasp8tm1ClieTgAlb1cre7Gsc
• liver inflammation_Casp8<tm1Clie>/Casp8<tm1Clie>,Tg(Alb1-cre)7Gsc/0
  http://metadb.riken.jp/0001860I129P2OlaHsdC57BL6FVBNCasp8tm1ClieCasp8tm1ClieTgAlb1cre7Gsc0Casp8tm1ClieTgAlb1cre7Gsc
• intrahepatic cholestasis_Casp8<tm1Clie>/Casp8<tm1Clie>,Ikbkg<tm1.1Chtr>/Ikbkg<tm1.1Chtr>,Tg(Alb1-cre)7Gsc/0
  http://metadb.riken.jp/0005415I129P2OlaHsdC57BL6FVBNCasp8tm1ClieCasp8tm1ClieIkbkgtm11ChtrIkbkgtm11ChtrTgAlb1cre7Gsc0Ikbkgtm11ChtrCasp8tm1ClieTgAlb1cre7Gsc
• decreased susceptibility to injury_Casp8<tm1Clie>/Casp8<tm1Clie>,Tg(Alb1-cre)7Gsc/0
  http://metadb.riken.jp/0005166I129P2OlaHsdC57BL6FVBNCasp8tm1ClieCasp8tm1ClieTgAlb1cre7Gsc0Casp8tm1ClieTgAlb1cre7Gsc
• increased circulating bilirubin level_Casp8<tm1Clie>/Casp8<tm1Clie>,Ikbkg<tm1.1Chtr>/Ikbkg<tm1.1Chtr>,Tg(Alb1-cre)7Gsc/0
  http://metadb.riken.jp/0005344I129P2OlaHsdC57BL6FVBNCasp8tm1ClieCasp8tm1ClieIkbkgtm11ChtrIkbkgtm11ChtrTgAlb1cre7Gsc0Ikbkgtm11ChtrCasp8tm1ClieTgAlb1cre7Gsc
• increased bile salt level_Casp8<tm1Clie>/Casp8<tm1Clie>,Ikbkg<tm1.1Chtr>/Ikbkg<tm1.1Chtr>,Tg(Alb1-cre)7Gsc/0
  http://metadb.riken.jp/0004789I129P2OlaHsdC57BL6FVBNCasp8tm1ClieCasp8tm1ClieIkbkgtm11ChtrIkbkgtm11ChtrTgAlb1cre7Gsc0Ikbkgtm11ChtrCasp8tm1ClieTgAlb1cre7Gsc
• abnormal circulating enzyme level_Casp8<tm1Clie>/Casp8<tm1Clie>,Tg(Alb1-cre)7Gsc/0
  http://metadb.riken.jp/0001570I129P2OlaHsdC57BL6FVBNCasp8tm1ClieCasp8tm1ClieTgAlb1cre7Gsc0Casp8tm1ClieTgAlb1cre7Gsc
• increased circulating alkaline phosphatase level_Casp8<tm1Clie>/Casp8<tm1Clie>,Ikbkg<tm1.1Chtr>/Ikbkg<tm1.1Chtr>,Tg(Alb1-cre)7Gsc/0
  http://metadb.riken.jp/0002968I129P2OlaHsdC57BL6FVBNCasp8tm1ClieCasp8tm1ClieIkbkgtm11ChtrIkbkgtm11ChtrTgAlb1cre7Gsc0Ikbkgtm11ChtrCasp8tm1ClieTgAlb1cre7Gsc
• decreased body size_Casp8<tm1Clie>/Casp8<tm1Clie>,Ikbkg<tm1.1Chtr>/Ikbkg<tm1.1Chtr>,Tg(Alb1-cre)7Gsc/0
  http://metadb.riken.jp/0001265I129P2OlaHsdC57BL6FVBNCasp8tm1ClieCasp8tm1ClieIkbkgtm11ChtrIkbkgtm11ChtrTgAlb1cre7Gsc0Ikbkgtm11ChtrCasp8tm1ClieTgAlb1cre7Gsc