decreased pancreatic beta cell number_Gadd45gip1<tm2Kong>/Gadd45gip1<tm2Kong>,Tg(Ins2-cre)25Mgn/0

http://metadb.riken.jp/0003339I129P2OlaHsdC57BL6DBAGadd45gip1tm2KongGadd45gip1tm2KongTgIns2cre25Mgn0Gadd45gip1tm2KongTgIns2cre25Mgn

decreased pancreatic beta cell number_Gadd45gip1<tm2Kong>/Gadd45gip1<tm2Kong>,Tg(Ins2-cre)25Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 25, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176225
• growth arrest and DNA-damage-inducible, gamma interacting protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1914947

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gadd45gip1<tm2Kong>/Gadd45gip1<tm2Kong>,Tg(Ins2-cre)25Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gadd45gip1<tm2Kong>|Tg(Ins2-cre)25Mgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased pancreatic beta cell number
  http://purl.obolibrary.org/obo/MP_0003339

文献

http://purl.org/net/cito/citesAsAuthority

• Yong Kyung. Kim, et.al., Disruption of CR6-interacting factor-1 (CRIF1) in mouse islet beta cells leads to mitochondrial diabetes with progressive beta cell failure., Diabetologia, 2015, 58
  http://rdf.ncbi.nlm.nih.gov/pubmed/25660120