decreased pancreatic beta cell number_Pdx1<tm1Cvw>/Pdx1<+>

http://metadb.riken.jp/0003339I129S1Sv129X1SvJC57BL6Pdx1tm1CvwPdx1Pdx1Pdx1tm1Cvw

decreased pancreatic beta cell number_Pdx1<tm1Cvw>/Pdx1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• pancreatic and duodenal homeobox 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:102851

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pdx1<tm1Cvw>/Pdx1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pdx1<+>|Pdx1<tm1Cvw>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased pancreatic beta cell number
  http://purl.obolibrary.org/obo/MP_0003339

文献

http://purl.org/net/cito/citesAsAuthority

• Kathryn C. Claiborn, et.al., Pcif1 modulates Pdx1 protein stability and pancreatic β cell function and survival in mice., The Journal of clinical investigation, 2010, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/20811152