astrocytosis_Tg(Prnp-PFN1*C71G)22Zxu/0,Tg(Thy1-PFN1*C71G)67Zxu/Tg(Thy1-PFN1*C71G)67Zxu

http://metadb.riken.jp/0003354IFVBNTgPrnpPFN1C71G22Zxu0TgThy1PFN1C71G67ZxuTgThy1PFN1C71G67ZxuTgPrnpPFN1C71G22ZxuTgThy1PFN1C71G67Zxu

astrocytosis_Tg(Prnp-PFN1*C71G)22Zxu/0,Tg(Thy1-PFN1*C71G)67Zxu/Tg(Thy1-PFN1*C71G)67Zxu

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 67, Zuoshang Xu
  http://metadb.riken.jp/db/mgi_rdf/MGI:5796271
• transgene insertion 22, Zuoshang Xu
  http://metadb.riken.jp/db/mgi_rdf/MGI:5796272

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Prnp-PFN1*C71G)22Zxu/0,Tg(Thy1-PFN1*C71G)67Zxu/Tg(Thy1-PFN1*C71G)67Zxu

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Prnp-PFN1*C71G)22Zxu|Tg(Thy1-PFN1*C71G)67Zxu

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• astrocytosis
  http://purl.obolibrary.org/obo/MP_0003354

文献

http://purl.org/net/cito/citesAsAuthority

• Chunxing. Yang, et.al., Mutant PFN1 causes ALS phenotypes and progressive motor neuron degeneration in mice by a gain of toxicity., Proceedings of the National Academy of Sciences of the United States of America, 2016, 113
  http://rdf.ncbi.nlm.nih.gov/pubmed/27681617