increased insulinoma incidence_Rps6kb2<tm1Gtho>/Rps6kb2<tm1Gtho>,Tg(Ins2-Akt1*)3Mbb/0

http://metadb.riken.jp/0003364B6CgRps6kb2tm1GthoTgIns2Akt13MbbRps6kb2tm1GthoRps6kb2tm1GthoTgIns2Akt13Mbb0Rps6kb2tm1GthoTgIns2Akt13Mbb

increased insulinoma incidence_Rps6kb2<tm1Gtho>/Rps6kb2<tm1Gtho>,Tg(Ins2-Akt1*)3Mbb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 3, Morris J Birnbaum
  http://metadb.riken.jp/db/mgi_rdf/MGI:5829192
• ribosomal protein S6 kinase, polypeptide 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1927343

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rps6kb2<tm1Gtho>/Rps6kb2<tm1Gtho>,Tg(Ins2-Akt1*)3Mbb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rps6kb2<tm1Gtho>|Tg(Ins2-Akt1*)3Mbb

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.Cg-Rps6kb2<tm1Gtho> Tg(Ins2-Akt1*)3Mbb

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased insulinoma incidence
  http://purl.obolibrary.org/obo/MP_0003364

文献

http://purl.org/net/cito/citesAsAuthority

• Samira. Alliouachene, et.al., Constitutively active Akt1 expression in mouse pancreas requires S6 kinase 1 for insulinoma formation., The Journal of clinical investigation, 2008, 118
  http://rdf.ncbi.nlm.nih.gov/pubmed/18846252