decreased width of hypertrophic chondrocyte zone_Acvr1<tm2.1Vlcg>/Acvr1<+>,Tg(Prrx1-cre)1Cjt/0

http://metadb.riken.jp/0003409IC57BL6JC57BL6NTacSJLJAcvr1tm21VlcgAcvr1TgPrrx1cre1Cjt0TgPrrx1cre1CjtAcvr1Acvr1tm21Vlcg

decreased width of hypertrophic chondrocyte zone_Acvr1<tm2.1Vlcg>/Acvr1<+>,Tg(Prrx1-cre)1Cjt/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Clifford J Tabin
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450928
• activin A receptor, type 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:87911

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Acvr1<tm2.1Vlcg>/Acvr1<+>,Tg(Prrx1-cre)1Cjt/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Prrx1-cre)1Cjt|Acvr1<+>|Acvr1<tm2.1Vlcg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6J * C57BL/6NTac * SJL/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased width of hypertrophic chondrocyte zone
  http://purl.obolibrary.org/obo/MP_0003409

文献

http://purl.org/net/cito/citesAsAuthority

• Salin A. Chakkalakal, et.al., Palovarotene Inhibits Heterotopic Ossification and Maintains Limb Mobility and Growth in Mice With the Human ACVR1(R206H) Fibrodysplasia Ossificans Progressiva (FOP) Mutation., Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2016, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/26896819