hair follicle degeneration_Tg(KRT14-rtTA)208Jek/Y,Tg(tetO-KLF4)32831Rup/0

http://metadb.riken.jp/0003413IC57BL6SJLTgKRT14rtTA208JekYTgtetOKLF432831Rup0TgKRT14rtTA208JekTgtetOKLF432831Rup

hair follicle degeneration_Tg(KRT14-rtTA)208Jek/Y,Tg(tetO-KLF4)32831Rup/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 208, Jeffrey E Kudlow
  http://metadb.riken.jp/db/mgi_rdf/MGI:3717742
• transgene insertion 32831, J Michael Ruppert
  http://metadb.riken.jp/db/mgi_rdf/MGI:3717761

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(KRT14-rtTA)208Jek/Y,Tg(tetO-KLF4)32831Rup/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(KRT14-rtTA)208Jek|Tg(tetO-KLF4)32831Rup

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• hair follicle degeneration
  http://purl.obolibrary.org/obo/MP_0003413

文献

http://purl.org/net/cito/citesAsAuthority

• K Wade. Foster, et.al., Induction of KLF4 in basal keratinocytes blocks the proliferation-differentiation switch and initiates squamous epithelial dysplasia., Oncogene, 2005, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/15674344