renal hypoplasia_Notch1<tm6.1Rko>/Notch1<+>,Notch2<tm3Grid>/Notch2<tm3Grid>,Tg(Pax3-cre)1Joe/0

http://metadb.riken.jp/0003446I129S1SvC57BL6SJLNotch1tm61RkoNotch1Notch2tm3GridNotch2tm3GridTgPax3cre1Joe0Notch2tm3GridNotch1TgPax3cre1JoeNotch1tm61Rko

renal hypoplasia_Notch1<tm6.1Rko>/Notch1<+>,Notch2<tm3Grid>/Notch2<tm3Grid>,Tg(Pax3-cre)1Joe/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• notch 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97364
• transgene insertion 1, Jonathan A Epstein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176201
• notch 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97363

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Notch1<tm6.1Rko>/Notch1<+>,Notch2<tm3Grid>/Notch2<tm3Grid>,Tg(Pax3-cre)1Joe/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Notch2<tm3Grid>|Notch1<+>|Tg(Pax3-cre)1Joe|Notch1<tm6.1Rko>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• renal hypoplasia
  http://purl.obolibrary.org/obo/MP_0003446

文献

http://purl.org/net/cito/citesAsAuthority

• Zhenyi. Liu, et.al., The extracellular domain of Notch2 increases its cell-surface abundance and ligand responsiveness during kidney development., Developmental cell, 2013, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/23806616