decreased tumor growth/size_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,X/Tg(Tyr-HRAS)60Lc

http://metadb.riken.jp/0003447I129SvC57BL6JCBAJSJLCdkn2atm1RdpCdkn2atm1RdpXTgTyrHRAS60LcTgTyrHRAS60LcCdkn2atm1Rdp

decreased tumor growth/size_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,X/Tg(Tyr-HRAS)60Lc

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 60, Lynda Chin
  http://metadb.riken.jp/db/mgi_rdf/MGI:2675988
• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,X/Tg(Tyr-HRAS)60Lc

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Tyr-HRAS)60Lc|Cdkn2a<tm1Rdp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6J * CBA/J * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased tumor growth/size
  http://purl.obolibrary.org/obo/MP_0003447

文献

http://purl.org/net/cito/citesAsAuthority

• K B. Monahan, et.al., Somatic p16(INK4a) loss accelerates melanomagenesis., Oncogene, 2010, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/20697345