abnormal tumor morphology_Ctsb<tm1Jde>/Ctsb<tm1Jde>,Ctsz<tm1Thre>/Ctsz<tm1Thre>,Tg(MMTV-PyVT)634Mul/0

http://metadb.riken.jp/0003448FVB129P2Ctsztm1ThreCtsbtm1JdeTgMMTVPyVT634MulCtsbtm1JdeCtsbtm1JdeCtsztm1ThreCtsztm1ThreTgMMTVPyVT634Mul0Ctsztm1ThreCtsbtm1JdeTgMMTVPyVT634Mul

abnormal tumor morphology_Ctsb<tm1Jde>/Ctsb<tm1Jde>,Ctsz<tm1Thre>/Ctsz<tm1Thre>,Tg(MMTV-PyVT)634Mul/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 634, William Muller
  http://metadb.riken.jp/db/mgi_rdf/MGI:2679594
• cathepsin Z
  http://metadb.riken.jp/db/mgi_rdf/MGI:1891190
• cathepsin B
  http://metadb.riken.jp/db/mgi_rdf/MGI:88561

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ctsb<tm1Jde>/Ctsb<tm1Jde>,Ctsz<tm1Thre>/Ctsz<tm1Thre>,Tg(MMTV-PyVT)634Mul/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ctsz<tm1Thre>|Ctsb<tm1Jde>|Tg(MMTV-PyVT)634Mul

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• FVB.129P2-Ctsz<tm1Thre> Ctsb<tm1Jde> Tg(MMTV-PyVT)634Mul

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• altered tumor morphology
  http://purl.obolibrary.org/obo/MP_0003448

文献

http://purl.org/net/cito/citesAsAuthority

• Lisa. Sevenich, et.al., Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20133781