Lisa. Sevenich, et.al., Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107

http://rdf.ncbi.nlm.nih.gov/pubmed/20133781

Lisa. Sevenich, et.al., Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ctsz<tm1Thre>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4436876

class

http://purl.org/net/cito/citesAsAuthority

• Ctsz<tm1Thre>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4436876

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal tumor morphology_Ctsb<tm1Jde>/Ctsb<tm1Jde>,Ctsz<tm1Thre>/Ctsz<tm1Thre>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0003448FVB129P2Ctsztm1ThreCtsbtm1JdeTgMMTVPyVT634MulCtsbtm1JdeCtsbtm1JdeCtsztm1ThreCtsztm1ThreTgMMTVPyVT634Mul0Ctsztm1ThreCtsbtm1JdeTgMMTVPyVT634Mul
• decreased apoptosis_Ctsz<tm1Thre>/Ctsz<tm1Thre>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0006043FVB129P2Ctsztm1ThreTgMMTVPyVT634MulCtsztm1ThreCtsztm1ThreTgMMTVPyVT634Mul0TgMMTVPyVT634MulCtsztm1Thre
• no abnormal phenotype detected_Ctsb<tm1Jde>/Ctsb<tm1Jde>,Ctsz<tm1Thre>/Ctsz<tm1Thre>
  http://metadb.riken.jp/0002169FVB129P2Ctsztm1ThreCtsbtm1JdeCtsbtm1JdeCtsbtm1JdeCtsztm1ThreCtsztm1ThreCtsbtm1JdeCtsztm1Thre
• decreased tumor growth/size_Ctsb<tm1Jde>/Ctsb<tm1Jde>,Ctsz<tm1Thre>/Ctsz<tm1Thre>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0003447FVB129P2Ctsztm1ThreCtsbtm1JdeTgMMTVPyVT634MulCtsbtm1JdeCtsbtm1JdeCtsztm1ThreCtsztm1ThreTgMMTVPyVT634Mul0Ctsztm1ThreCtsbtm1JdeTgMMTVPyVT634Mul
• increased mammary gland tumor incidence_Ctsb<tm1Jde>/Ctsb<tm1Jde>,Ctsz<tm1Thre>/Ctsz<tm1Thre>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0010299FVB129P2Ctsztm1ThreCtsbtm1JdeTgMMTVPyVT634MulCtsbtm1JdeCtsbtm1JdeCtsztm1ThreCtsztm1ThreTgMMTVPyVT634Mul0Ctsztm1ThreCtsbtm1JdeTgMMTVPyVT634Mul
• increased mammary gland tumor incidence_Ctsb<tm1Jde>/Ctsb<tm1Jde>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0010299FVB129P2Ctsbtm1JdeTgMMTVPyVT634MulCtsbtm1JdeCtsbtm1JdeTgMMTVPyVT634Mul0Ctsbtm1JdeTgMMTVPyVT634Mul
• increased tumor latency_Ctsz<tm1Thre>/Ctsz<tm1Thre>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0009828FVB129P2Ctsztm1ThreTgMMTVPyVT634MulCtsztm1ThreCtsztm1ThreTgMMTVPyVT634Mul0TgMMTVPyVT634MulCtsztm1Thre
• decreased tumor growth/size_Ctsb<tm1Jde>/Ctsb<tm1Jde>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0003447FVB129P2Ctsbtm1JdeTgMMTVPyVT634MulCtsbtm1JdeCtsbtm1JdeTgMMTVPyVT634Mul0Ctsbtm1JdeTgMMTVPyVT634Mul
• decreased metastatic potential_Ctsb<tm1Jde>/Ctsb<tm1Jde>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0001273FVB129P2Ctsbtm1JdeTgMMTVPyVT634MulCtsbtm1JdeCtsbtm1JdeTgMMTVPyVT634Mul0Ctsbtm1JdeTgMMTVPyVT634Mul
• increased tumor latency_Ctsb<tm1Jde>/Ctsb<tm1Jde>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0009828FVB129P2Ctsbtm1JdeTgMMTVPyVT634MulCtsbtm1JdeCtsbtm1JdeTgMMTVPyVT634Mul0Ctsbtm1JdeTgMMTVPyVT634Mul
• abnormal tumor morphology_Ctsb<tm1Jde>/Ctsb<tm1Jde>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0003448FVB129P2Ctsbtm1JdeTgMMTVPyVT634MulCtsbtm1JdeCtsbtm1JdeTgMMTVPyVT634Mul0Ctsbtm1JdeTgMMTVPyVT634Mul
• no abnormal phenotype detected_Ctsz<tm1Thre>/Ctsz<tm1Thre>
  http://metadb.riken.jp/0002169FVB129P2Ctsztm1ThreCtsztm1ThreCtsztm1ThreCtsztm1Thre
• decreased metastatic potential_Ctsz<tm1Thre>/Ctsz<tm1Thre>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0001273FVB129P2Ctsztm1ThreTgMMTVPyVT634MulCtsztm1ThreCtsztm1ThreTgMMTVPyVT634Mul0TgMMTVPyVT634MulCtsztm1Thre
• increased mammary gland tumor incidence_Ctsz<tm1Thre>/Ctsz<tm1Thre>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0010299FVB129P2Ctsztm1ThreTgMMTVPyVT634MulCtsztm1ThreCtsztm1ThreTgMMTVPyVT634Mul0TgMMTVPyVT634MulCtsztm1Thre
• increased tumor growth/size_Ctsz<tm1Thre>/Ctsz<tm1Thre>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0003721FVB129P2Ctsztm1ThreTgMMTVPyVT634MulCtsztm1ThreCtsztm1ThreTgMMTVPyVT634Mul0TgMMTVPyVT634MulCtsztm1Thre
• decreased apoptosis_Ctsb<tm1Jde>/Ctsb<tm1Jde>,Ctsz<tm1Thre>/Ctsz<tm1Thre>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0006043FVB129P2Ctsztm1ThreCtsbtm1JdeTgMMTVPyVT634MulCtsbtm1JdeCtsbtm1JdeCtsztm1ThreCtsztm1ThreTgMMTVPyVT634Mul0Ctsztm1ThreCtsbtm1JdeTgMMTVPyVT634Mul
• increased tumor latency_Ctsb<tm1Jde>/Ctsb<tm1Jde>,Ctsz<tm1Thre>/Ctsz<tm1Thre>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0009828FVB129P2Ctsztm1ThreCtsbtm1JdeTgMMTVPyVT634MulCtsbtm1JdeCtsbtm1JdeCtsztm1ThreCtsztm1ThreTgMMTVPyVT634Mul0Ctsztm1ThreCtsbtm1JdeTgMMTVPyVT634Mul
• decreased metastatic potential_Ctsb<tm1Jde>/Ctsb<tm1Jde>,Ctsz<tm1Thre>/Ctsz<tm1Thre>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0001273FVB129P2Ctsztm1ThreCtsbtm1JdeTgMMTVPyVT634MulCtsbtm1JdeCtsbtm1JdeCtsztm1ThreCtsztm1ThreTgMMTVPyVT634Mul0Ctsztm1ThreCtsbtm1JdeTgMMTVPyVT634Mul

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD00369
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD00369