abnormal tumor morphology_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brd>/Trp53<+>,Tg(Rbp3-cre)1Brn/0

http://metadb.riken.jp/0003448I129129S7SvEvBrdC57BL6FVBNRb1tm2BrnRb1tm2BrnTrp53tm1BrdTrp53TgRbp3cre1Brn0Trp53Rb1tm2BrnTrp53tm1BrdTgRbp3cre1Brn

abnormal tumor morphology_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brd>/Trp53<+>,Tg(Rbp3-cre)1Brn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• RB transcriptional corepressor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97874
• transgene insertion 1, Anton Berns
  http://metadb.riken.jp/db/mgi_rdf/MGI:2445225

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brd>/Trp53<+>,Tg(Rbp3-cre)1Brn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<+>|Rb1<tm2Brn>|Trp53<tm1Brd>|Tg(Rbp3-cre)1Brn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129S7/SvEvBrd * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• altered tumor morphology
  http://purl.obolibrary.org/obo/MP_0003448

文献

http://purl.org/net/cito/citesAsAuthority

• Marc. Vooijs, et.al., Tumor formation in mice with somatic inactivation of the retinoblastoma gene in interphotoreceptor retinol binding protein-expressing cells., Oncogene, 2002, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/12096340