Marc. Vooijs, et.al., Tumor formation in mice with somatic inactivation of the retinoblastoma gene in interphotoreceptor retinol binding protein-expressing cells., Oncogene, 2002, 21

http://rdf.ncbi.nlm.nih.gov/pubmed/12096340

Marc. Vooijs, et.al., Tumor formation in mice with somatic inactivation of the retinoblastoma gene in interphotoreceptor retinol binding protein-expressing cells., Oncogene, 2002, 21

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Rb1<tm2.1Brn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4415315

class

http://purl.org/net/cito/citesAsAuthority

• Rb1<tm2.1Brn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4415315

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased tumor incidence_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brd>/Trp53<+>,Tg(Rbp3-cre)1Brn/0
  http://metadb.riken.jp/0002020I129129S7SvEvBrdC57BL6FVBNRb1tm2BrnRb1tm2BrnTrp53tm1BrdTrp53TgRbp3cre1Brn0Trp53Rb1tm2BrnTrp53tm1BrdTgRbp3cre1Brn
• increased pituitary adenohypophysis tumor incidence_Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(Rbp3-cre)1Brn/0
  http://metadb.riken.jp/0010350I129FVBNRb1tm2BrnRb1tm2BrnTgRbp3cre1Brn0TgRbp3cre1BrnRb1tm2Brn
• lethality throughout fetal growth and development, complete penetrance_Rb1<tm2.1Brn>/Rb1<tm2.1Brn>
  http://metadb.riken.jp/0011099NSRb1tm21BrnRb1tm21BrnRb1tm21Brn
• increased pituitary melanotroph tumor incidence_Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(Rbp3-cre)1Brn/0
  http://metadb.riken.jp/0010351I129FVBNRb1tm2BrnRb1tm2BrnTgRbp3cre1Brn0TgRbp3cre1BrnRb1tm2Brn
• abnormal tumor morphology_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brd>/Trp53<+>,Tg(Rbp3-cre)1Brn/0
  http://metadb.riken.jp/0003448I129129S7SvEvBrdC57BL6FVBNRb1tm2BrnRb1tm2BrnTrp53tm1BrdTrp53TgRbp3cre1Brn0Trp53Rb1tm2BrnTrp53tm1BrdTgRbp3cre1Brn