increased thyroid adenoma incidence_E2f1<tm1Njd>/E2f1<+>,Rb1<tm1Tyj>/Rb1<+>

http://metadb.riken.jp/0003496E129S2SvPasorI129S2SvPasC57BL6E2f1tm1NjdE2f1Rb1tm1TyjRb1Rb1tm1TyjE2f1tm1NjdRb1E2f1

increased thyroid adenoma incidence_E2f1<tm1Njd>/E2f1<+>,Rb1<tm1Tyj>/Rb1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• RB transcriptional corepressor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97874
• E2F transcription factor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:101941

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• E2f1<tm1Njd>/E2f1<+>,Rb1<tm1Tyj>/Rb1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rb1<tm1Tyj>|E2f1<tm1Njd>|Rb1<+>|E2f1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: 129S2/SvPas or (involves: 129S2/SvPas * C57BL/6)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased thyroid adenoma incidence
  http://purl.obolibrary.org/obo/MP_0003496

文献

http://purl.org/net/cito/citesAsAuthority

• L. Yamasaki, et.al., Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice., Nature genetics, 1998, 18
  http://rdf.ncbi.nlm.nih.gov/pubmed/9537419