L. Yamasaki, et.al., Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice., Nature genetics, 1998, 18

http://rdf.ncbi.nlm.nih.gov/pubmed/9537419

L. Yamasaki, et.al., Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice., Nature genetics, 1998, 18

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• premature death_E2f1<tm1Njd>/E2f1<+>,Rb1<tm1Tyj>/Rb1<+>
  http://metadb.riken.jp/0002083E129S2SvPasorI129S2SvPasC57BL6E2f1tm1NjdE2f1Rb1tm1TyjRb1Rb1tm1TyjE2f1tm1NjdRb1E2f1
• premature death_E2f1<tm1Njd>/E2f1<tm1Njd>,Rb1<tm1Tyj>/Rb1<+>
  http://metadb.riken.jp/0002083E129S2SvPasorI129S2SvPasC57BL6E2f1tm1NjdE2f1tm1NjdRb1tm1TyjRb1E2f1tm1NjdRb1Rb1tm1Tyj
• prenatal lethality, complete penetrance_E2f1<tm1Njd>/E2f1<+>,Rb1<tm1Tyj>/Rb1<tm1Tyj>
  http://metadb.riken.jp/0011091E129S2SvPasorI129S2SvPasC57BL6E2f1tm1NjdE2f1Rb1tm1TyjRb1tm1TyjRb1tm1TyjE2f1tm1NjdE2f1
• prenatal lethality, complete penetrance_E2f1<tm1Njd>/E2f1<tm1Njd>,Rb1<tm1Tyj>/Rb1<tm1Tyj>
  http://metadb.riken.jp/0011091E129S2SvPasorI129S2SvPasC57BL6E2f1tm1NjdE2f1tm1NjdRb1tm1TyjRb1tm1TyjE2f1tm1NjdRb1tm1Tyj
• increased hemangioma incidence_E2f1<tm1Njd>/E2f1<tm1Njd>,Rb1<tm1Tyj>/Rb1<+>
  http://metadb.riken.jp/0002947E129S2SvPasorI129S2SvPasC57BL6E2f1tm1NjdE2f1tm1NjdRb1tm1TyjRb1E2f1tm1NjdRb1Rb1tm1Tyj
• increased pituitary gland tumor incidence_E2f1<tm1Njd>/E2f1<tm1Njd>,Rb1<tm1Tyj>/Rb1<+>
  http://metadb.riken.jp/0010320E129S2SvPasorI129S2SvPasC57BL6E2f1tm1NjdE2f1tm1NjdRb1tm1TyjRb1E2f1tm1NjdRb1Rb1tm1Tyj
• increased thyroid adenoma incidence_E2f1<tm1Njd>/E2f1<+>,Rb1<tm1Tyj>/Rb1<+>
  http://metadb.riken.jp/0003496E129S2SvPasorI129S2SvPasC57BL6E2f1tm1NjdE2f1Rb1tm1TyjRb1Rb1tm1TyjE2f1tm1NjdRb1E2f1
• abnormal thyroid gland morphology_E2f1<tm1Njd>/E2f1<tm1Njd>,Rb1<tm1Tyj>/Rb1<+>
  http://metadb.riken.jp/0000681E129S2SvPasorI129S2SvPasC57BL6E2f1tm1NjdE2f1tm1NjdRb1tm1TyjRb1E2f1tm1NjdRb1Rb1tm1Tyj
• adrenal medulla hyperplasia_E2f1<tm1Njd>/E2f1<tm1Njd>,Rb1<tm1Tyj>/Rb1<+>
  http://metadb.riken.jp/0008301E129S2SvPasorI129S2SvPasC57BL6E2f1tm1NjdE2f1tm1NjdRb1tm1TyjRb1E2f1tm1NjdRb1Rb1tm1Tyj
• uterine hemorrhage_E2f1<tm1Njd>/E2f1<tm1Njd>,Rb1<tm1Tyj>/Rb1<+>
  http://metadb.riken.jp/0004898E129S2SvPasorI129S2SvPasC57BL6E2f1tm1NjdE2f1tm1NjdRb1tm1TyjRb1E2f1tm1NjdRb1Rb1tm1Tyj
• increased tumor incidence_E2f1<tm1Njd>/E2f1<+>,Rb1<tm1Tyj>/Rb1<+>
  http://metadb.riken.jp/0002020E129S2SvPasorI129S2SvPasC57BL6E2f1tm1NjdE2f1Rb1tm1TyjRb1Rb1tm1TyjE2f1tm1NjdRb1E2f1
• increased thyroid adenoma incidence_E2f1<tm1Njd>/E2f1<tm1Njd>,Rb1<tm1Tyj>/Rb1<+>
  http://metadb.riken.jp/0003496E129S2SvPasorI129S2SvPasC57BL6E2f1tm1NjdE2f1tm1NjdRb1tm1TyjRb1E2f1tm1NjdRb1Rb1tm1Tyj