thyroid gland hyperplasia_Cdkn1b<tm1Ako>/Cdkn1b<tm1Ako>,Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Tg(TPO-cre)1Shk/0

http://metadb.riken.jp/0003498129S1CgCdkn1btm1AkoPtentm21PppTgTPOcre1ShkCdkn1btm1AkoCdkn1btm1AkoPtentm21PppPtentm21PppTgTPOcre1Shk0TgTPOcre1ShkPtentm21PppCdkn1btm1Ako

thyroid gland hyperplasia_Cdkn1b<tm1Ako>/Cdkn1b<tm1Ako>,Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Tg(TPO-cre)1Shk/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Shioko Kimura
  http://metadb.riken.jp/db/mgi_rdf/MGI:3653643
• cyclin-dependent kinase inhibitor 1B
  http://metadb.riken.jp/db/mgi_rdf/MGI:104565
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn1b<tm1Ako>/Cdkn1b<tm1Ako>,Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Tg(TPO-cre)1Shk/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(TPO-cre)1Shk|Pten<tm2.1Ppp>|Cdkn1b<tm1Ako>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• 129S1.Cg-Cdkn1b<tm1Ako> Pten<tm2.1Ppp> Tg(TPO-cre)1Shk

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• thyroid gland hyperplasia
  http://purl.obolibrary.org/obo/MP_0003498

文献

http://purl.org/net/cito/citesAsAuthority

• V G. Antico-Arciuch, et.al., Cross-talk between PI3K and estrogen in the mouse thyroid predisposes to the development of follicular carcinomas with a higher incidence in females., Oncogene, 2010, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/20676139