V G. Antico-Arciuch, et.al., Cross-talk between PI3K and estrogen in the mouse thyroid predisposes to the development of follicular carcinomas with a higher incidence in females., Oncogene, 2010, 29

http://rdf.ncbi.nlm.nih.gov/pubmed/20676139

V G. Antico-Arciuch, et.al., Cross-talk between PI3K and estrogen in the mouse thyroid predisposes to the development of follicular carcinomas with a higher incidence in females., Oncogene, 2010, 29

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• premature death_Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Tg(TPO-cre)1Shk/0
  http://metadb.riken.jp/0002083129S1CgPtentm21PppTgTPOcre1ShkPtentm21PppPtentm21PppTgTPOcre1Shk0Ptentm21PppTgTPOcre1Shk
• decreased thyroid-stimulating hormone level_Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Tg(TPO-cre)1Shk/0
  http://metadb.riken.jp/0005134129S1CgPtentm21PppTgTPOcre1ShkPtentm21PppPtentm21PppTgTPOcre1Shk0Ptentm21PppTgTPOcre1Shk
• increased thyroid adenoma incidence_Cdkn1b<tm1Ako>/Cdkn1b<+>,Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Tg(TPO-cre)1Shk/0
  http://metadb.riken.jp/0003496129S1CgCdkn1btm1AkoPtentm21PppTgTPOcre1ShkCdkn1btm1AkoCdkn1bPtentm21PppPtentm21PppTgTPOcre1Shk0Ptentm21PppCdkn1btm1AkoTgTPOcre1ShkCdkn1b
• increased thyroid carcinoma incidence_Cdkn1b<tm1Ako>/Cdkn1b<+>,Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Tg(TPO-cre)1Shk/0
  http://metadb.riken.jp/0010346129S1CgCdkn1btm1AkoPtentm21PppTgTPOcre1ShkCdkn1btm1AkoCdkn1bPtentm21PppPtentm21PppTgTPOcre1Shk0Ptentm21PppCdkn1btm1AkoTgTPOcre1ShkCdkn1b
• increased thyroxine level_Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Tg(TPO-cre)1Shk/0
  http://metadb.riken.jp/0005470129S1CgPtentm21PppTgTPOcre1ShkPtentm21PppPtentm21PppTgTPOcre1Shk0Ptentm21PppTgTPOcre1Shk
• thyroid gland hyperplasia_Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Tg(TPO-cre)1Shk/0
  http://metadb.riken.jp/0003498129S1CgPtentm21PppTgTPOcre1ShkPtentm21PppPtentm21PppTgTPOcre1Shk0Ptentm21PppTgTPOcre1Shk
• premature death_Cdkn1b<tm1Ako>/Cdkn1b<+>,Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Tg(TPO-cre)1Shk/0
  http://metadb.riken.jp/0002083129S1CgCdkn1btm1AkoPtentm21PppTgTPOcre1ShkCdkn1btm1AkoCdkn1bPtentm21PppPtentm21PppTgTPOcre1Shk0Ptentm21PppCdkn1btm1AkoTgTPOcre1ShkCdkn1b
• thyroid gland hyperplasia_Cdkn1b<tm1Ako>/Cdkn1b<tm1Ako>,Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Tg(TPO-cre)1Shk/0
  http://metadb.riken.jp/0003498129S1CgCdkn1btm1AkoPtentm21PppTgTPOcre1ShkCdkn1btm1AkoCdkn1btm1AkoPtentm21PppPtentm21PppTgTPOcre1Shk0TgTPOcre1ShkPtentm21PppCdkn1btm1Ako
• premature death_Cdkn1b<tm1Ako>/Cdkn1b<tm1Ako>,Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Tg(TPO-cre)1Shk/0
  http://metadb.riken.jp/0002083129S1CgCdkn1btm1AkoPtentm21PppTgTPOcre1ShkCdkn1btm1AkoCdkn1btm1AkoPtentm21PppPtentm21PppTgTPOcre1Shk0TgTPOcre1ShkPtentm21PppCdkn1btm1Ako
• increased thyroid carcinoma incidence_Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Tg(TPO-cre)1Shk/0
  http://metadb.riken.jp/0010346129S1CgPtentm21PppTgTPOcre1ShkPtentm21PppPtentm21PppTgTPOcre1Shk0Ptentm21PppTgTPOcre1Shk
• respiratory distress_Cdkn1b<tm1Ako>/Cdkn1b<tm1Ako>,Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Tg(TPO-cre)1Shk/0
  http://metadb.riken.jp/0001954129S1CgCdkn1btm1AkoPtentm21PppTgTPOcre1ShkCdkn1btm1AkoCdkn1btm1AkoPtentm21PppPtentm21PppTgTPOcre1Shk0TgTPOcre1ShkPtentm21PppCdkn1btm1Ako
• increased thyroid adenoma incidence_Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Tg(TPO-cre)1Shk/0
  http://metadb.riken.jp/0003496129S1CgPtentm21PppTgTPOcre1ShkPtentm21PppPtentm21PppTgTPOcre1Shk0Ptentm21PppTgTPOcre1Shk