thyroid gland hyperplasia_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Nkx2-1-cre)2Sand/0

http://metadb.riken.jp/0003498I129S4SvJaeBALBcC57BL6Ptentm1HwuPtentm1HwuTgNkx21cre2Sand0TgNkx21cre2SandPtentm1Hwu

thyroid gland hyperplasia_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Nkx2-1-cre)2Sand/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 2, Stewart Anderson
  http://metadb.riken.jp/db/mgi_rdf/MGI:3773079
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Nkx2-1-cre)2Sand/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Nkx2-1-cre)2Sand|Pten<tm1Hwu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * BALB/c * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• thyroid gland hyperplasia
  http://purl.obolibrary.org/obo/MP_0003498

文献

http://purl.org/net/cito/citesAsAuthority

• Caterina. Tiozzo, et.al., Embryonic epithelial Pten deletion through Nkx2.1-cre leads to thyroid tumorigenesis in a strain-dependent manner., Endocrine-related cancer, 2012, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/22167068