abnormal pancreatic beta cell physiology_Sh2b1<tm2.1Lr>/Sh2b1<tm2.1Lr>,Tg(Pdx1-cre)89.1Dam/0

http://metadb.riken.jp/0003562I129S1Sv129X1SvJC57BL6CBASJLSh2b1tm21LrSh2b1tm21LrTgPdx1cre891Dam0TgPdx1cre891DamSh2b1tm21Lr

abnormal pancreatic beta cell physiology_Sh2b1<tm2.1Lr>/Sh2b1<tm2.1Lr>,Tg(Pdx1-cre)89.1Dam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• SH2B adaptor protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1201407
• transgene insertion 89.1, Douglas A Melton
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684318

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sh2b1<tm2.1Lr>/Sh2b1<tm2.1Lr>,Tg(Pdx1-cre)89.1Dam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Pdx1-cre)89.1Dam|Sh2b1<tm2.1Lr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal pancreatic beta cell physiology
  http://purl.obolibrary.org/obo/MP_0003562

文献

http://purl.org/net/cito/citesAsAuthority

• Zheng. Chen, et.al., SH2B1 in β-cells regulates glucose metabolism by promoting β-cell survival and islet expansion., Diabetes, 2014, 63
  http://rdf.ncbi.nlm.nih.gov/pubmed/24150605