abnormal insulin secretion_Ffar2<tm2Soff>/Ffar2<tm2Soff>,Ffar3<tm2.1Soff>/Ffar3<tm2.1Soff>,Tg(Ins2-cre)25Mgn/0

http://metadb.riken.jp/0003564I129S4SvJaeC57BL6DBAFfar2tm2SoffFfar2tm2SoffFfar3tm21SoffFfar3tm21SoffTgIns2cre25Mgn0Ffar2tm2SoffTgIns2cre25MgnFfar3tm21Soff

abnormal insulin secretion_Ffar2<tm2Soff>/Ffar2<tm2Soff>,Ffar3<tm2.1Soff>/Ffar3<tm2.1Soff>,Tg(Ins2-cre)25Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 25, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176225
• free fatty acid receptor 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:2441731
• free fatty acid receptor 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:2685324

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ffar2<tm2Soff>/Ffar2<tm2Soff>,Ffar3<tm2.1Soff>/Ffar3<tm2.1Soff>,Tg(Ins2-cre)25Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ffar2<tm2Soff>|Tg(Ins2-cre)25Mgn|Ffar3<tm2.1Soff>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal insulin secretion
  http://purl.obolibrary.org/obo/MP_0003564

文献

http://purl.org/net/cito/citesAsAuthority

• Cong. Tang, et.al., Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes., Nature medicine, 2015, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/25581519