Cong. Tang, et.al., Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes., Nature medicine, 2015, 21

http://rdf.ncbi.nlm.nih.gov/pubmed/25581519

Cong. Tang, et.al., Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes., Nature medicine, 2015, 21

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ffar3<tm2.1Soff>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5770448
• Ffar3<tm1Soff>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5770446
• Ffar2<tm2Soff>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5770447
• Ffar2<tm1Soff>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5770445
• Del(7Ffar2-Ffar3)1Soff
  http://metadb.riken.jp/db/mgi_rdf/MGI:5770474

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased circulating free fatty acid level_Ffar2<tm2Soff>/Ffar2<tm2Soff>,Ffar3<tm2.1Soff>/Ffar3<tm2.1Soff>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0002702I129S4SvJaeC57BL6DBAFfar2tm2SoffFfar2tm2SoffFfar3tm21SoffFfar3tm21SoffTgIns2cre25Mgn0Ffar2tm2SoffTgIns2cre25MgnFfar3tm21Soff
• increased circulating insulin level_Ffar2<tm2Soff>/Ffar2<tm2Soff>,Ffar3<tm2.1Soff>/Ffar3<tm2.1Soff>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0002079I129S4SvJaeC57BL6DBAFfar2tm2SoffFfar2tm2SoffFfar3tm21SoffFfar3tm21SoffTgIns2cre25Mgn0Ffar2tm2SoffTgIns2cre25MgnFfar3tm21Soff
• abnormal insulin secretion_Ffar2<tm2Soff>/Ffar2<tm2Soff>,Ffar3<tm2.1Soff>/Ffar3<tm2.1Soff>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0003564I129S4SvJaeC57BL6DBAFfar2tm2SoffFfar2tm2SoffFfar3tm21SoffFfar3tm21SoffTgIns2cre25Mgn0Ffar2tm2SoffTgIns2cre25MgnFfar3tm21Soff
• increased circulating insulin level_Ffar3<tm1Soff>/Ffar3<tm1Soff>
  http://metadb.riken.jp/0002079B6129Ffar3tm1SoffFfar3tm1SoffFfar3tm1SoffFfar3tm1Soff
• increased circulating insulin level_Del(7Ffar2-Ffar3)1Soff/Del(7Ffar2-Ffar3)1Soff
  http://metadb.riken.jp/0002079I129S4SvJaeC57BL6Del7Ffar2Ffar31SoffDel7Ffar2Ffar31SoffDel7Ffar2Ffar31Soff
• increased circulating insulin level_Ffar2<tm1Soff>/Ffar2<tm1Soff>
  http://metadb.riken.jp/0002079B6129Ffar2tm1SoffFfar2tm1SoffFfar2tm1SoffFfar2tm1Soff
• improved glucose tolerance_Ffar2<tm2Soff>/Ffar2<tm2Soff>,Ffar3<tm2.1Soff>/Ffar3<tm2.1Soff>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005292I129S4SvJaeC57BL6DBAFfar2tm2SoffFfar2tm2SoffFfar3tm21SoffFfar3tm21SoffTgIns2cre25Mgn0Ffar2tm2SoffTgIns2cre25MgnFfar3tm21Soff
• improved glucose tolerance_Del(7Ffar2-Ffar3)1Soff/Del(7Ffar2-Ffar3)1Soff
  http://metadb.riken.jp/0005292I129S4SvJaeC57BL6Del7Ffar2Ffar31SoffDel7Ffar2Ffar31SoffDel7Ffar2Ffar31Soff
• abnormal insulin secretion_Del(7Ffar2-Ffar3)1Soff/Del(7Ffar2-Ffar3)1Soff
  http://metadb.riken.jp/0003564I129S4SvJaeC57BL6Del7Ffar2Ffar31SoffDel7Ffar2Ffar31SoffDel7Ffar2Ffar31Soff
• decreased circulating free fatty acid level_Del(7Ffar2-Ffar3)1Soff/Del(7Ffar2-Ffar3)1Soff
  http://metadb.riken.jp/0002702I129S4SvJaeC57BL6Del7Ffar2Ffar31SoffDel7Ffar2Ffar31SoffDel7Ffar2Ffar31Soff

class

http://purl.org/net/cito/citesAsAuthority

• Ffar3<tm2.1Soff>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5770448
• Ffar3<tm1Soff>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5770446
• Ffar2<tm2Soff>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5770447
• Ffar2<tm1Soff>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5770445
• Del(7Ffar2-Ffar3)1Soff
  http://metadb.riken.jp/db/mgi_rdf/MGI:5770474