spleen atrophy_Col1a1<tm2(tetO-Pou5f1)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>

http://metadb.riken.jp/0003643I129S4SvJaeC57BL6Col1a1tm2tetOPou5f1JaeCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1tm2tetOPou5f1JaeGtROSA26Sortm1rtTAM2JaeCol1a1GtROSA26Sor

spleen atrophy_Col1a1<tm2(tetO-Pou5f1)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• collagen, type I, alpha 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88467
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Col1a1<tm2(tetO-Pou5f1)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Col1a1<tm2(tetO-Pou5f1)Jae>|Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>|Col1a1<+>|Gt(ROSA)26Sor<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• spleen atrophy
  http://purl.obolibrary.org/obo/MP_0003643

文献

http://purl.org/net/cito/citesAsAuthority

• Konrad. Hochedlinger, et.al., Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues., Cell, 2005, 121
  http://rdf.ncbi.nlm.nih.gov/pubmed/15882627