Konrad. Hochedlinger, et.al., Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues., Cell, 2005, 121

http://rdf.ncbi.nlm.nih.gov/pubmed/15882627

Konrad. Hochedlinger, et.al., Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues., Cell, 2005, 121

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3702294
• Col1a1<tm2(tetO-Pou5f1)Jae>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3702325

class

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3702294
• Col1a1<tm2(tetO-Pou5f1)Jae>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3702325

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal epidermal layer morphology_Col1a1<tm2(tetO-Pou5f1)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0001216I129S4SvJaeC57BL6Col1a1tm2tetOPou5f1JaeCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1tm2tetOPou5f1JaeGtROSA26Sortm1rtTAM2JaeCol1a1GtROSA26Sor
• abnormal stomach glandular epithelium morphology_Col1a1<tm2(tetO-Pou5f1)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000473I129S4SvJaeC57BL6Col1a1tm2tetOPou5f1JaeCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1tm2tetOPou5f1JaeGtROSA26Sortm1rtTAM2JaeCol1a1GtROSA26Sor
• abnormal stomach epithelium morphology_Col1a1<tm2(tetO-Pou5f1)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000471I129S4SvJaeC57BL6Col1a1tm2tetOPou5f1JaeCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1tm2tetOPou5f1JaeGtROSA26Sortm1rtTAM2JaeCol1a1GtROSA26Sor
• abnormal intermediate gastric gland morphology_Col1a1<tm2(tetO-Pou5f1)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0010796I129S4SvJaeC57BL6Col1a1tm2tetOPou5f1JaeCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1tm2tetOPou5f1JaeGtROSA26Sortm1rtTAM2JaeCol1a1GtROSA26Sor
• abnormal cell proliferation_Col1a1<tm2(tetO-Pou5f1)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000350I129S4SvJaeC57BL6Col1a1tm2tetOPou5f1JaeCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1tm2tetOPou5f1JaeGtROSA26Sortm1rtTAM2JaeCol1a1GtROSA26Sor
• lethargy_Col1a1<tm2(tetO-Pou5f1)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005202I129S4SvJaeC57BL6Col1a1tm2tetOPou5f1JaeCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1tm2tetOPou5f1JaeGtROSA26Sortm1rtTAM2JaeCol1a1GtROSA26Sor
• thymus atrophy_Col1a1<tm2(tetO-Pou5f1)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0003644I129S4SvJaeC57BL6Col1a1tm2tetOPou5f1JaeCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1tm2tetOPou5f1JaeGtROSA26Sortm1rtTAM2JaeCol1a1GtROSA26Sor
• spleen atrophy_Col1a1<tm2(tetO-Pou5f1)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0003643I129S4SvJaeC57BL6Col1a1tm2tetOPou5f1JaeCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1tm2tetOPou5f1JaeGtROSA26Sortm1rtTAM2JaeCol1a1GtROSA26Sor
• abnormal stomach mucosa morphology_Col1a1<tm2(tetO-Pou5f1)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0010792I129S4SvJaeC57BL6Col1a1tm2tetOPou5f1JaeCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1tm2tetOPou5f1JaeGtROSA26Sortm1rtTAM2JaeCol1a1GtROSA26Sor
• stomach epithelial hyperplasia_Col1a1<tm2(tetO-Pou5f1)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005493I129S4SvJaeC57BL6Col1a1tm2tetOPou5f1JaeCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1tm2tetOPou5f1JaeGtROSA26Sortm1rtTAM2JaeCol1a1GtROSA26Sor
• abnormal hair follicle morphology_Col1a1<tm2(tetO-Pou5f1)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000377I129S4SvJaeC57BL6Col1a1tm2tetOPou5f1JaeCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1tm2tetOPou5f1JaeGtROSA26Sortm1rtTAM2JaeCol1a1GtROSA26Sor
• increased skin tumor incidence_Col1a1<tm2(tetO-Pou5f1)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0010300I129S4SvJaeC57BL6Col1a1tm2tetOPou5f1JaeCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1tm2tetOPou5f1JaeGtROSA26Sortm1rtTAM2JaeCol1a1GtROSA26Sor
• abnormal small intestine morphology_Col1a1<tm2(tetO-Pou5f1)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000496I129S4SvJaeC57BL6Col1a1tm2tetOPou5f1JaeCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1tm2tetOPou5f1JaeGtROSA26Sortm1rtTAM2JaeCol1a1GtROSA26Sor
• dehydration_Col1a1<tm2(tetO-Pou5f1)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0001429I129S4SvJaeC57BL6Col1a1tm2tetOPou5f1JaeCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1tm2tetOPou5f1JaeGtROSA26Sortm1rtTAM2JaeCol1a1GtROSA26Sor
• abnormal intestinal epithelium morphology_Col1a1<tm2(tetO-Pou5f1)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000488I129S4SvJaeC57BL6Col1a1tm2tetOPou5f1JaeCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1tm2tetOPou5f1JaeGtROSA26Sortm1rtTAM2JaeCol1a1GtROSA26Sor
• abnormal forestomach morphology_Col1a1<tm2(tetO-Pou5f1)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0010784I129S4SvJaeC57BL6Col1a1tm2tetOPou5f1JaeCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1tm2tetOPou5f1JaeGtROSA26Sortm1rtTAM2JaeCol1a1GtROSA26Sor
• premature death_Col1a1<tm2(tetO-Pou5f1)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0002083I129S4SvJaeC57BL6Col1a1tm2tetOPou5f1JaeCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1tm2tetOPou5f1JaeGtROSA26Sortm1rtTAM2JaeCol1a1GtROSA26Sor