increased pancreatic beta cell number_Cdk4<tm1.1Bbd>/Cdk4<+>

http://metadb.riken.jp/0003645I129S1Sv129X1SvJICRCdk4tm11BbdCdk4Cdk4tm11BbdCdk4

increased pancreatic beta cell number_Cdk4<tm1.1Bbd>/Cdk4<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:88357

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdk4<tm1.1Bbd>/Cdk4<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdk4<tm1.1Bbd>|Cdk4<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * ICR

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pancreatic beta cell number
  http://purl.obolibrary.org/obo/MP_0003645

文献

http://purl.org/net/cito/citesAsAuthority

• S G. Rane, et.al., Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia., Nature genetics, 1999, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/10319860