decreased heart right ventricle size_Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>,Isl1<tm1(cre)Tmj>/Isl1<+>

http://metadb.riken.jp/0003649I129X1SvJC57BL6Nkx25tm1KrcNkx25tm1KrcIsl1tm1creTmjIsl1Isl1tm1creTmjNkx25tm1KrcIsl1

decreased heart right ventricle size_Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>,Isl1<tm1(cre)Tmj>/Isl1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ISL1 transcription factor, LIM/homeodomain
  http://metadb.riken.jp/db/mgi_rdf/MGI:101791
• NK2 homeobox 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:97350

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>,Isl1<tm1(cre)Tmj>/Isl1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Isl1<tm1(cre)Tmj>|Nkx2-5<tm1Krc>|Isl1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased heart right ventricle size
  http://purl.obolibrary.org/obo/MP_0003649

文献

http://purl.org/net/cito/citesAsAuthority

• Linda. Cambier, et.al., Nkx2-5 regulates cardiac growth through modulation of Wnt signaling by R-spondin3., Development (Cambridge, England), 2014, 141
  http://rdf.ncbi.nlm.nih.gov/pubmed/25053429