Linda. Cambier, et.al., Nkx2-5 regulates cardiac growth through modulation of Wnt signaling by R-spondin3., Development (Cambridge, England), 2014, 141

http://rdf.ncbi.nlm.nih.gov/pubmed/25053429

Linda. Cambier, et.al., Nkx2-5 regulates cardiac growth through modulation of Wnt signaling by R-spondin3., Development (Cambridge, England), 2014, 141

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Rspo3<tm1Arte>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5643687

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• vasculature congestion_Rspo3<tm1Arte>/Rspo3<tm1Arte>,Isl1<tm1(cre)Sev>/Isl1<+>
  http://metadb.riken.jp/0000255I129C57BL6Rspo3tm1ArteRspo3tm1ArteIsl1tm1creSevIsl1Isl1tm1creSevIsl1Rspo3tm1Arte
• double outlet right ventricle_Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>,Isl1<tm1(cre)Tmj>/Isl1<+>
  http://metadb.riken.jp/0000284I129X1SvJC57BL6Nkx25tm1KrcNkx25tm1KrcIsl1tm1creTmjIsl1Isl1tm1creTmjNkx25tm1KrcIsl1
• double outlet right ventricle_Rspo3<tm1Arte>/Rspo3<tm1Arte>,Isl1<tm1(cre)Tmj>/Isl1<+>
  http://metadb.riken.jp/0000284I129X1SvJC57BL6Rspo3tm1ArteRspo3tm1ArteIsl1tm1creTmjIsl1Isl1tm1creTmjRspo3tm1ArteIsl1
• cyanosis_Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>,Isl1<tm1(cre)Tmj>/Isl1<+>
  http://metadb.riken.jp/0001575I129X1SvJC57BL6Nkx25tm1KrcNkx25tm1KrcIsl1tm1creTmjIsl1Isl1tm1creTmjNkx25tm1KrcIsl1
• pericardial edema_Rspo3<tm1Arte>/Rspo3<tm1Arte>,Isl1<tm1(cre)Sev>/Isl1<+>
  http://metadb.riken.jp/0001787I129C57BL6Rspo3tm1ArteRspo3tm1ArteIsl1tm1creSevIsl1Isl1tm1creSevIsl1Rspo3tm1Arte
• pericardial edema_Rspo3<tm1Arte>/Rspo3<tm1Arte>,Isl1<tm1(cre)Tmj>/Isl1<+>
  http://metadb.riken.jp/0001787I129X1SvJC57BL6Rspo3tm1ArteRspo3tm1ArteIsl1tm1creTmjIsl1Isl1tm1creTmjRspo3tm1ArteIsl1
他20件を見る
• perinatal lethality_Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>,Isl1<tm1(cre)Tmj>/Isl1<+>
  http://metadb.riken.jp/0002081I129X1SvJC57BL6Nkx25tm1KrcNkx25tm1KrcIsl1tm1creTmjIsl1Isl1tm1creTmjNkx25tm1KrcIsl1
• abnormal myocardial trabeculae morphology_Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>,Isl1<tm1(cre)Tmj>/Isl1<+>
  http://metadb.riken.jp/0002189I129X1SvJC57BL6Nkx25tm1KrcNkx25tm1KrcIsl1tm1creTmjIsl1Isl1tm1creTmjNkx25tm1KrcIsl1
• persistent truncus arteriosis_Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>,Isl1<tm1(cre)Tmj>/Isl1<+>
  http://metadb.riken.jp/0002633I129X1SvJC57BL6Nkx25tm1KrcNkx25tm1KrcIsl1tm1creTmjIsl1Isl1tm1creTmjNkx25tm1KrcIsl1
• thin myocardium_Rspo3<tm1Arte>/Rspo3<tm1Arte>,Isl1<tm1(cre)Sev>/Isl1<+>
  http://metadb.riken.jp/0002652I129C57BL6Rspo3tm1ArteRspo3tm1ArteIsl1tm1creSevIsl1Isl1tm1creSevIsl1Rspo3tm1Arte
• decreased heart right ventricle size_Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>,Isl1<tm1(cre)Tmj>/Isl1<+>
  http://metadb.riken.jp/0003649I129X1SvJC57BL6Nkx25tm1KrcNkx25tm1KrcIsl1tm1creTmjIsl1Isl1tm1creTmjNkx25tm1KrcIsl1
• decreased heart right ventricle size_Rspo3<tm1Arte>/Rspo3<tm1Arte>,Isl1<tm1(cre)Tmj>/Isl1<+>
  http://metadb.riken.jp/0003649I129X1SvJC57BL6Rspo3tm1ArteRspo3tm1ArteIsl1tm1creTmjIsl1Isl1tm1creTmjRspo3tm1ArteIsl1
• absent heart right ventricle_Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>,Isl1<tm1(cre)Sev>/Isl1<+>
  http://metadb.riken.jp/0003872I129C57BL6Nkx25tm1KrcNkx25tm1KrcIsl1tm1creSevIsl1Isl1Isl1tm1creSevNkx25tm1Krc
• absent heart right ventricle_Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>,Tg(Mef2c-cre)#Blk/0
  http://metadb.riken.jp/0003872I129C57BL6Nkx25tm1KrcNkx25tm1KrcTgMef2ccreBlk0TgMef2ccreBlkNkx25tm1Krc
• abnormal heart right ventricle morphology_Rspo3<tm1Arte>/Rspo3<tm1Arte>,Isl1<tm1(cre)Sev>/Isl1<+>
  http://metadb.riken.jp/0003920I129C57BL6Rspo3tm1ArteRspo3tm1ArteIsl1tm1creSevIsl1Isl1tm1creSevIsl1Rspo3tm1Arte
• abnormal heart right ventricle morphology_Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>,Isl1<tm1(cre)Tmj>/Isl1<+>
  http://metadb.riken.jp/0003920I129X1SvJC57BL6Nkx25tm1KrcNkx25tm1KrcIsl1tm1creTmjIsl1Isl1tm1creTmjNkx25tm1KrcIsl1
• abnormal cardiac outflow tract development_Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>,Isl1<tm1(cre)Sev>/Isl1<+>
  http://metadb.riken.jp/0006126I129C57BL6Nkx25tm1KrcNkx25tm1KrcIsl1tm1creSevIsl1Isl1Isl1tm1creSevNkx25tm1Krc
• abnormal cardiac outflow tract development_Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>,Tg(Mef2c-cre)#Blk/0
  http://metadb.riken.jp/0006126I129C57BL6Nkx25tm1KrcNkx25tm1KrcTgMef2ccreBlk0TgMef2ccreBlkNkx25tm1Krc
• abnormal cardiac outflow tract development_Rspo3<tm1Arte>/Rspo3<tm1Arte>,Isl1<tm1(cre)Sev>/Isl1<+>
  http://metadb.riken.jp/0006126I129C57BL6Rspo3tm1ArteRspo3tm1ArteIsl1tm1creSevIsl1Isl1tm1creSevIsl1Rspo3tm1Arte
• abnormal cardiac outflow tract development_Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>,Isl1<tm1(cre)Tmj>/Isl1<+>
  http://metadb.riken.jp/0006126I129X1SvJC57BL6Nkx25tm1KrcNkx25tm1KrcIsl1tm1creTmjIsl1Isl1tm1creTmjNkx25tm1KrcIsl1
• heart right ventricle hypoplasia_Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>,Isl1<tm1(cre)Tmj>/Isl1<+>
  http://metadb.riken.jp/0010422I129X1SvJC57BL6Nkx25tm1KrcNkx25tm1KrcIsl1tm1creTmjIsl1Isl1tm1creTmjNkx25tm1KrcIsl1
• abnormal conotruncal ridge morphology_Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>,Isl1<tm1(cre)Tmj>/Isl1<+>
  http://metadb.riken.jp/0010585I129X1SvJC57BL6Nkx25tm1KrcNkx25tm1KrcIsl1tm1creTmjIsl1Isl1tm1creTmjNkx25tm1KrcIsl1
• embryonic lethality during organogenesis, complete penetrance_Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>,Isl1<tm1(cre)Sev>/Isl1<+>
  http://metadb.riken.jp/0011098I129C57BL6Nkx25tm1KrcNkx25tm1KrcIsl1tm1creSevIsl1Isl1Isl1tm1creSevNkx25tm1Krc
• embryonic lethality during organogenesis, complete penetrance_Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>,Tg(Mef2c-cre)#Blk/0
  http://metadb.riken.jp/0011098I129C57BL6Nkx25tm1KrcNkx25tm1KrcTgMef2ccreBlk0TgMef2ccreBlkNkx25tm1Krc
• embryonic lethality during organogenesis, complete penetrance_Rspo3<tm1Arte>/Rspo3<tm1Arte>,Isl1<tm1(cre)Sev>/Isl1<+>
  http://metadb.riken.jp/0011098I129C57BL6Rspo3tm1ArteRspo3tm1ArteIsl1tm1creSevIsl1Isl1tm1creSevIsl1Rspo3tm1Arte
• lethality throughout fetal growth and development, complete penetrance_Rspo3<tm1Arte>/Rspo3<tm1Arte>,Isl1<tm1(cre)Tmj>/Isl1<+>
  http://metadb.riken.jp/0011099I129X1SvJC57BL6Rspo3tm1ArteRspo3tm1ArteIsl1tm1creTmjIsl1Isl1tm1creTmjRspo3tm1ArteIsl1

class

http://purl.org/net/cito/citesAsAuthority

• Rspo3<tm1Arte>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5643687