increased hemangiosarcoma incidence_Trp53bp2<tm1Xlu>/Trp53bp2<+>

http://metadb.riken.jp/0003667I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2Trp53bp2Trp53bp2tm1Xlu

increased hemangiosarcoma incidence_Trp53bp2<tm1Xlu>/Trp53bp2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53 binding protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:2138319

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53bp2<tm1Xlu>/Trp53bp2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53bp2<+>|Trp53bp2<tm1Xlu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hemangiosarcoma incidence
  http://purl.obolibrary.org/obo/MP_0003667

文献

http://purl.org/net/cito/citesAsAuthority

• Virginie. Vives, et.al., ASPP2 is a haploinsufficient tumor suppressor that cooperates with p53 to suppress tumor growth., Genes & development, 2006, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/16702401