Virginie. Vives, et.al., ASPP2 is a haploinsufficient tumor suppressor that cooperates with p53 to suppress tumor growth., Genes & development, 2006, 20

http://rdf.ncbi.nlm.nih.gov/pubmed/16702401

Virginie. Vives, et.al., ASPP2 is a haploinsufficient tumor suppressor that cooperates with p53 to suppress tumor growth., Genes & development, 2006, 20

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3625686

class

http://purl.org/net/cito/citesAsAuthority

• Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3625686

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased squamous cell carcinoma incidence_Trp53bp2<tm1Xlu>/Trp53bp2<+>
  http://metadb.riken.jp/0004207I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2Trp53bp2Trp53bp2tm1Xlu
• increased lymphoma incidence_Trp53bp2<tm1Xlu>/Trp53bp2<+>
  http://metadb.riken.jp/0012431I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2Trp53bp2Trp53bp2tm1Xlu
• embryonic lethality during organogenesis, complete penetrance_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0011098I129S2SvPas129S6SvEvTacC57BL6JTrp53tm1TyjTrp53tm1TyjTrp53bp2tm1XluTrp53bp2tm1XluTrp53tm1TyjTrp53bp2tm1Xlu
• increased hemangiosarcoma incidence_Trp53bp2<tm1Xlu>/Trp53bp2<+>
  http://metadb.riken.jp/0003667I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2Trp53bp2Trp53bp2tm1Xlu
• increased rhabdomyosarcoma incidence_Trp53bp2<tm1Xlu>/Trp53bp2<+>
  http://metadb.riken.jp/0002036I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2Trp53bp2Trp53bp2tm1Xlu
• abnormal tumor incidence_Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0002019I129S2SvPasC57BL6JTrp53tm1TyjTrp53Trp53tm1TyjTrp53
• increased tumor incidence_Trp53bp2<tm1Xlu>/Trp53bp2<+>
  http://metadb.riken.jp/0002020I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2Trp53bp2Trp53bp2tm1Xlu
• decreased body size_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0001265I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• postnatal lethality, complete penetrance_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0011085I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• increased T cell derived lymphoma incidence_Trp53bp2<tm1Xlu>/Trp53bp2<+>
  http://metadb.riken.jp/0002024I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2Trp53bp2Trp53bp2tm1Xlu
• increased incidence of tumors by ionizing radiation induction_Trp53bp2<tm1Xlu>/Trp53bp2<+>
  http://metadb.riken.jp/0004500I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2Trp53bp2Trp53bp2tm1Xlu
• prenatal lethality, incomplete penetrance_Trp53<tm1Tyj>/Trp53<+>,Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0011101I129S2SvPas129S6SvEvTacC57BL6JTrp53tm1TyjTrp53Trp53bp2tm1XluTrp53bp2tm1XluTrp53Trp53tm1TyjTrp53bp2tm1Xlu
• abnormal tumor latency_Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0010307I129S2SvPasC57BL6JTrp53tm1TyjTrp53Trp53tm1TyjTrp53
• increased tumor incidence_Trp53<tm1Tyj>/Trp53<+>,Trp53bp2<tm1Xlu>/Trp53bp2<+>
  http://metadb.riken.jp/0002020I129S2SvPas129S6SvEvTacC57BL6JTrp53tm1TyjTrp53Trp53bp2tm1XluTrp53bp2Trp53bp2Trp53tm1TyjTrp53Trp53bp2tm1Xlu
• domed cranium_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0000440I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• increased lymphoma incidence_Trp53<tm1Tyj>/Trp53<+>,Trp53bp2<tm1Xlu>/Trp53bp2<+>
  http://metadb.riken.jp/0012431I129S2SvPas129S6SvEvTacC57BL6JTrp53tm1TyjTrp53Trp53bp2tm1XluTrp53bp2Trp53bp2Trp53tm1TyjTrp53Trp53bp2tm1Xlu
• perinatal lethality, incomplete penetrance_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0011090I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD27768
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD27768