kidney cysts_Col1a1<tm2(tetO-LIN28B)Gqda>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/Gt(ROSA)26Sor<+>,Tg(Six2-EGFP/cre)1Amc/0

http://metadb.riken.jp/0003675I129S1Sv129S4SvJae129X1SvJC57BL6CD1Col1a1tm2tetOLIN28BGqdaCol1a1GtROSA26Sortm1rtTAEGFPNagyGtROSA26SorTgSix2EGFPcre1Amc0GtROSA26SorCol1a1tm2tetOLIN28BGqdaCol1a1GtROSA26Sortm1rtTAEGFPNagyTgSix2EGFPcre1Amc

kidney cysts_Col1a1<tm2(tetO-LIN28B)Gqda>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/Gt(ROSA)26Sor<+>,Tg(Six2-EGFP/cre)1Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• collagen, type I, alpha 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88467
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 1, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:3845227

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Col1a1<tm2(tetO-LIN28B)Gqda>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/Gt(ROSA)26Sor<+>,Tg(Six2-EGFP/cre)1Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<+>|Col1a1<tm2(tetO-LIN28B)Gqda>|Col1a1<+>|Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>|Tg(Six2-EGFP/cre)1Amc

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * CD-1

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• kidney cysts
  http://purl.obolibrary.org/obo/MP_0003675

文献

http://purl.org/net/cito/citesAsAuthority

• Achia. Urbach, et.al., Lin28 sustains early renal progenitors and induces Wilms tumor., Genes & development, 2014, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/24732380