kidney cysts_Cdkn1a<tm1Tyj>/Cdkn1a<tm1Tyj>,Fah<tm1Mgo>/Fah<tm1Mgo>

http://metadb.riken.jp/0003675I129S2SvPas129S7SvEvBrdC57BL6Cdkn1atm1TyjCdkn1atm1TyjFahtm1MgoFahtm1MgoCdkn1atm1TyjFahtm1Mgo

kidney cysts_Cdkn1a<tm1Tyj>/Cdkn1a<tm1Tyj>,Fah<tm1Mgo>/Fah<tm1Mgo>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• fumarylacetoacetate hydrolase
  http://metadb.riken.jp/db/mgi_rdf/MGI:95482
• cyclin-dependent kinase inhibitor 1A (P21)
  http://metadb.riken.jp/db/mgi_rdf/MGI:104556

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn1a<tm1Tyj>/Cdkn1a<tm1Tyj>,Fah<tm1Mgo>/Fah<tm1Mgo>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdkn1a<tm1Tyj>|Fah<tm1Mgo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• kidney cysts
  http://purl.obolibrary.org/obo/MP_0003675

文献

http://purl.org/net/cito/citesAsAuthority

• Holger. Willenbring, et.al., Loss of p21 permits carcinogenesis from chronically damaged liver and kidney epithelial cells despite unchecked apoptosis., Cancer cell, 2008, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/18598944