Holger. Willenbring, et.al., Loss of p21 permits carcinogenesis from chronically damaged liver and kidney epithelial cells despite unchecked apoptosis., Cancer cell, 2008, 14

http://rdf.ncbi.nlm.nih.gov/pubmed/18598944

Holger. Willenbring, et.al., Loss of p21 permits carcinogenesis from chronically damaged liver and kidney epithelial cells despite unchecked apoptosis., Cancer cell, 2008, 14

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased sensitivity to induced morbidity/mortality_Fah<tm1Mgo>/Fah<tm1Mgo>
  http://metadb.riken.jp/0009763I129S7SvEvBrdC57BL6Fahtm1MgoFahtm1MgoFahtm1Mgo
• abnormal liver physiology_Fah<tm1Mgo>/Fah<tm1Mgo>
  http://metadb.riken.jp/0000609I129S7SvEvBrdC57BL6Fahtm1MgoFahtm1MgoFahtm1Mgo
• dilated proximal convoluted tubules_Cdkn1a<tm1Tyj>/Cdkn1a<tm1Tyj>,Fah<tm1Mgo>/Fah<tm1Mgo>
  http://metadb.riken.jp/0009050I129S2SvPas129S7SvEvBrdC57BL6Cdkn1atm1TyjCdkn1atm1TyjFahtm1MgoFahtm1MgoCdkn1atm1TyjFahtm1Mgo
• abnormal liver regeneration_Fah<tm1Mgo>/Fah<tm1Mgo>
  http://metadb.riken.jp/0002658I129S7SvEvBrdC57BL6Fahtm1MgoFahtm1MgoFahtm1Mgo
• decreased liver regeneration_Fah<tm1Mgo>/Fah<tm1Mgo>
  http://metadb.riken.jp/0005517I129S7SvEvBrdC57BL6Fahtm1MgoFahtm1MgoFahtm1Mgo
• increased hepatocyte apoptosis_Cdkn1a<tm1Tyj>/Cdkn1a<tm1Tyj>,Fah<tm1Mgo>/Fah<tm1Mgo>
  http://metadb.riken.jp/0003887I129S2SvPas129S7SvEvBrdC57BL6Cdkn1atm1TyjCdkn1atm1TyjFahtm1MgoFahtm1MgoCdkn1atm1TyjFahtm1Mgo
• abnormal hepatocyte morphology_Cdkn1a<tm1Tyj>/Cdkn1a<tm1Tyj>,Fah<tm1Mgo>/Fah<tm1Mgo>
  http://metadb.riken.jp/0000607I129S2SvPas129S7SvEvBrdC57BL6Cdkn1atm1TyjCdkn1atm1TyjFahtm1MgoFahtm1MgoCdkn1atm1TyjFahtm1Mgo
• weight loss_Cdkn1a<tm1Tyj>/Cdkn1a<tm1Tyj>,Fah<tm1Mgo>/Fah<tm1Mgo>
  http://metadb.riken.jp/0001263I129S2SvPas129S7SvEvBrdC57BL6Cdkn1atm1TyjCdkn1atm1TyjFahtm1MgoFahtm1MgoCdkn1atm1TyjFahtm1Mgo
• increased hepatocellular carcinoma incidence_Fah<tm1Mgo>/Fah<tm1Mgo>
  http://metadb.riken.jp/0003331I129S7SvEvBrdC57BL6Fahtm1MgoFahtm1MgoFahtm1Mgo
• increased susceptibility to injury_Fah<tm1Mgo>/Fah<tm1Mgo>
  http://metadb.riken.jp/0005165I129S7SvEvBrdC57BL6Fahtm1MgoFahtm1MgoFahtm1Mgo
• increased renal carcinoma incidence_Cdkn1a<tm1Tyj>/Cdkn1a<tm1Tyj>,Fah<tm1Mgo>/Fah<tm1Mgo>
  http://metadb.riken.jp/0010384I129S2SvPas129S7SvEvBrdC57BL6Cdkn1atm1TyjCdkn1atm1TyjFahtm1MgoFahtm1MgoCdkn1atm1TyjFahtm1Mgo
• abnormal hepatocyte morphology_Fah<tm1Mgo>/Fah<tm1Mgo>
  http://metadb.riken.jp/0000607I129S7SvEvBrdC57BL6Fahtm1MgoFahtm1MgoFahtm1Mgo
• aminoaciduria_Fah<tm1Mgo>/Fah<tm1Mgo>
  http://metadb.riken.jp/0003311I129S7SvEvBrdC57BL6Fahtm1MgoFahtm1MgoFahtm1Mgo
• enlarged kidney_Fah<tm1Mgo>/Fah<tm1Mgo>
  http://metadb.riken.jp/0003068I129S7SvEvBrdC57BL6Fahtm1MgoFahtm1MgoFahtm1Mgo
• decreased hepatocyte proliferation_Fah<tm1Mgo>/Fah<tm1Mgo>
  http://metadb.riken.jp/0004001I129S7SvEvBrdC57BL6Fahtm1MgoFahtm1MgoFahtm1Mgo
• abnormal liver physiology_Cdkn1a<tm1Tyj>/Cdkn1a<tm1Tyj>,Fah<tm1Mgo>/Fah<tm1Mgo>
  http://metadb.riken.jp/0000609I129S2SvPas129S7SvEvBrdC57BL6Cdkn1atm1TyjCdkn1atm1TyjFahtm1MgoFahtm1MgoCdkn1atm1TyjFahtm1Mgo
• increased hepatocyte proliferation_Cdkn1a<tm1Tyj>/Cdkn1a<tm1Tyj>,Fah<tm1Mgo>/Fah<tm1Mgo>
  http://metadb.riken.jp/0003893I129S2SvPas129S7SvEvBrdC57BL6Cdkn1atm1TyjCdkn1atm1TyjFahtm1MgoFahtm1MgoCdkn1atm1TyjFahtm1Mgo
• weight loss_Fah<tm1Mgo>/Fah<tm1Mgo>
  http://metadb.riken.jp/0001263I129S7SvEvBrdC57BL6Fahtm1MgoFahtm1MgoFahtm1Mgo
• increased hepatocellular carcinoma incidence_Cdkn1a<tm1Tyj>/Cdkn1a<tm1Tyj>,Fah<tm1Mgo>/Fah<tm1Mgo>
  http://metadb.riken.jp/0003331I129S2SvPas129S7SvEvBrdC57BL6Cdkn1atm1TyjCdkn1atm1TyjFahtm1MgoFahtm1MgoCdkn1atm1TyjFahtm1Mgo
• kidney cysts_Cdkn1a<tm1Tyj>/Cdkn1a<tm1Tyj>,Fah<tm1Mgo>/Fah<tm1Mgo>
  http://metadb.riken.jp/0003675I129S2SvPas129S7SvEvBrdC57BL6Cdkn1atm1TyjCdkn1atm1TyjFahtm1MgoFahtm1MgoCdkn1atm1TyjFahtm1Mgo