elevated level of mitotic sister chromatid exchange_Pot1a<tm1Schg>/Pot1a<tm1.1Schg>,Trp53<tm1Tyj>/Trp53<tm1Tyj>

http://metadb.riken.jp/0003701I129S2SvPas129S7SvEvBrdC57BL6Pot1atm1SchgPot1atm11SchgTrp53tm1TyjTrp53tm1TyjPot1atm1SchgPot1atm11SchgTrp53tm1Tyj

elevated level of mitotic sister chromatid exchange_Pot1a<tm1Schg>/Pot1a<tm1.1Schg>,Trp53<tm1Tyj>/Trp53<tm1Tyj>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• protection of telomeres 1A
  http://metadb.riken.jp/db/mgi_rdf/MGI:2141503

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pot1a<tm1Schg>/Pot1a<tm1.1Schg>,Trp53<tm1Tyj>/Trp53<tm1Tyj>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pot1a<tm1Schg>|Pot1a<tm1.1Schg>|Trp53<tm1Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• elevated level of mitotic sister chromatid exchange
  http://purl.obolibrary.org/obo/MP_0003701

文献

http://purl.org/net/cito/citesAsAuthority

• Ling. Wu, et.al., Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres., Cell, 2006, 126
  http://rdf.ncbi.nlm.nih.gov/pubmed/16839876