Ling. Wu, et.al., Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres., Cell, 2006, 126

http://rdf.ncbi.nlm.nih.gov/pubmed/16839876

Ling. Wu, et.al., Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres., Cell, 2006, 126

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pot1a<tm1.1Schg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3665307
• Pot1a<tm1Schg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3665306

class

http://purl.org/net/cito/citesAsAuthority

• Pot1a<tm1.1Schg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3665307
• Pot1a<tm1Schg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3665306

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal cell physiology_Pot1a<tm1Schg>/Pot1a<tm1.1Schg>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0005621I129S2SvPas129S7SvEvBrdC57BL6Pot1atm1SchgPot1atm11SchgTrp53tm1TyjTrp53tm1TyjPot1atm1SchgPot1atm11SchgTrp53tm1Tyj
• abnormal chromosome morphology_Pot1a<tm1Schg>/Pot1a<tm1.1Schg>
  http://metadb.riken.jp/0003702I129S7SvEvBrdC57BL6Pot1atm1SchgPot1atm11SchgPot1atm1SchgPot1atm11Schg
• elevated level of mitotic sister chromatid exchange_Pot1a<tm1Schg>/Pot1a<tm1.1Schg>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0003701I129S2SvPas129S7SvEvBrdC57BL6Pot1atm1SchgPot1atm11SchgTrp53tm1TyjTrp53tm1TyjPot1atm1SchgPot1atm11SchgTrp53tm1Tyj
• abnormal telomere length_Pot1a<tm1Schg>/Pot1a<tm1.1Schg>
  http://metadb.riken.jp/0003155I129S7SvEvBrdC57BL6Pot1atm1SchgPot1atm11SchgPot1atm1SchgPot1atm11Schg
• decreased cell proliferation_Pot1a<tm1.1Schg>/Pot1a<tm1.1Schg>
  http://metadb.riken.jp/0000352I129S7SvEvBrdC57BL6Pot1atm11SchgPot1atm11SchgPot1atm11Schg
• chromosome breakage_Pot1a<tm1Schg>/Pot1a<tm1.1Schg>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0004028I129S2SvPas129S7SvEvBrdC57BL6Pot1atm1SchgPot1atm11SchgTrp53tm1TyjTrp53tm1TyjPot1atm1SchgPot1atm11SchgTrp53tm1Tyj
• decreased cell proliferation_Pot1a<tm1Schg>/Pot1a<tm1.1Schg>
  http://metadb.riken.jp/0000352I129S7SvEvBrdC57BL6Pot1atm1SchgPot1atm11SchgPot1atm1SchgPot1atm11Schg
• abnormal chromosome morphology_Pot1a<tm1Schg>/Pot1a<tm1.1Schg>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0003702I129S2SvPas129S7SvEvBrdC57BL6Pot1atm1SchgPot1atm11SchgTrp53tm1TyjTrp53tm1TyjPot1atm1SchgPot1atm11SchgTrp53tm1Tyj

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD24742
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD24742
• CD02043
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD02043