pallor_Prmt5<tm2c(EUCOMM)Wtsi>/Prmt5<tm2c(EUCOMM)Wtsi>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>

http://metadb.riken.jp/0003717I129P2OlaHsd129S1SvlmJC57BL6BrdC57BL6NSJLPrmt5tm2cEUCOMMWtsiPrmt5tm2cEUCOMMWtsiGtROSA26Sortm2creERT2BrnGtROSA26SorGtROSA26SorPrmt5tm2cEUCOMMWtsiGtROSA26Sortm2creERT2Brn

pallor_Prmt5<tm2c(EUCOMM)Wtsi>/Prmt5<tm2c(EUCOMM)Wtsi>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• protein arginine N-methyltransferase 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:1351645

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Prmt5<tm2c(EUCOMM)Wtsi>/Prmt5<tm2c(EUCOMM)Wtsi>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<+>|Prmt5<tm2c(EUCOMM)Wtsi>|Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/SvlmJ * C57BL/6Brd * C57BL/6N * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• pallor
  http://purl.obolibrary.org/obo/MP_0003717

文献

http://purl.org/net/cito/citesAsAuthority

• Marco. Bezzi, et.al., Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery., Genes & development, 2013, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/24013503