Marco. Bezzi, et.al., Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery., Genes & development, 2013, 27

http://rdf.ncbi.nlm.nih.gov/pubmed/24013503

Marco. Bezzi, et.al., Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery., Genes & development, 2013, 27

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Prmt5<tm2c(EUCOMM)Wtsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5546597

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• tremors_Prmt5<tm2c(EUCOMM)Wtsi>/Prmt5<tm2c(EUCOMM)Wtsi>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000745B6CgPrmt5tm2cEUCOMMWtsiTgNescre1KlnPrmt5tm2cEUCOMMWtsiPrmt5tm2cEUCOMMWtsiTgNescre1Kln0TgNescre1KlnPrmt5tm2cEUCOMMWtsi
• decreased brain size_Prmt5<tm2c(EUCOMM)Wtsi>/Prmt5<tm2c(EUCOMM)Wtsi>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000774B6CgPrmt5tm2cEUCOMMWtsiTgNescre1KlnPrmt5tm2cEUCOMMWtsiPrmt5tm2cEUCOMMWtsiTgNescre1Kln0TgNescre1KlnPrmt5tm2cEUCOMMWtsi
• abnormal lateral ventricle morphology_Prmt5<tm2c(EUCOMM)Wtsi>/Prmt5<tm2c(EUCOMM)Wtsi>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000823B6CgPrmt5tm2cEUCOMMWtsiTgNescre1KlnPrmt5tm2cEUCOMMWtsiPrmt5tm2cEUCOMMWtsiTgNescre1Kln0TgNescre1KlnPrmt5tm2cEUCOMMWtsi
• abnormal cerebellum external granule cell layer morphology_Prmt5<tm2c(EUCOMM)Wtsi>/Prmt5<tm2c(EUCOMM)Wtsi>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000872B6CgPrmt5tm2cEUCOMMWtsiTgNescre1KlnPrmt5tm2cEUCOMMWtsiPrmt5tm2cEUCOMMWtsiTgNescre1Kln0TgNescre1KlnPrmt5tm2cEUCOMMWtsi
• impaired balance_Prmt5<tm2c(EUCOMM)Wtsi>/Prmt5<tm2c(EUCOMM)Wtsi>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001525B6CgPrmt5tm2cEUCOMMWtsiTgNescre1KlnPrmt5tm2cEUCOMMWtsiPrmt5tm2cEUCOMMWtsiTgNescre1Kln0TgNescre1KlnPrmt5tm2cEUCOMMWtsi
• decreased embryo size_Prmt5<tm2c(EUCOMM)Wtsi>/Prmt5<tm2c(EUCOMM)Wtsi>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0001698I129P2OlaHsd129S1SvlmJC57BL6BrdC57BL6NSJLPrmt5tm2cEUCOMMWtsiPrmt5tm2cEUCOMMWtsiGtROSA26Sortm2creERT2BrnGtROSA26SorGtROSA26SorPrmt5tm2cEUCOMMWtsiGtROSA26Sortm2creERT2Brn
他12件を見る
• decreased brain weight_Prmt5<tm2c(EUCOMM)Wtsi>/Prmt5<tm2c(EUCOMM)Wtsi>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002175B6CgPrmt5tm2cEUCOMMWtsiTgNescre1KlnPrmt5tm2cEUCOMMWtsiPrmt5tm2cEUCOMMWtsiTgNescre1Kln0TgNescre1KlnPrmt5tm2cEUCOMMWtsi
• akinesia_Prmt5<tm2c(EUCOMM)Wtsi>/Prmt5<tm2c(EUCOMM)Wtsi>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002690B6CgPrmt5tm2cEUCOMMWtsiTgNescre1KlnPrmt5tm2cEUCOMMWtsiPrmt5tm2cEUCOMMWtsiTgNescre1Kln0TgNescre1KlnPrmt5tm2cEUCOMMWtsi
• increased neuron apoptosis_Prmt5<tm2c(EUCOMM)Wtsi>/Prmt5<tm2c(EUCOMM)Wtsi>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0003203B6CgPrmt5tm2cEUCOMMWtsiTgNescre1KlnPrmt5tm2cEUCOMMWtsiPrmt5tm2cEUCOMMWtsiTgNescre1Kln0TgNescre1KlnPrmt5tm2cEUCOMMWtsi
• pallor_Prmt5<tm2c(EUCOMM)Wtsi>/Prmt5<tm2c(EUCOMM)Wtsi>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0003717I129P2OlaHsd129S1SvlmJC57BL6BrdC57BL6NSJLPrmt5tm2cEUCOMMWtsiPrmt5tm2cEUCOMMWtsiGtROSA26Sortm2creERT2BrnGtROSA26SorGtROSA26SorPrmt5tm2cEUCOMMWtsiGtROSA26Sortm2creERT2Brn
• embryonic growth retardation_Prmt5<tm2c(EUCOMM)Wtsi>/Prmt5<tm2c(EUCOMM)Wtsi>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0003984I129P2OlaHsd129S1SvlmJC57BL6BrdC57BL6NSJLPrmt5tm2cEUCOMMWtsiPrmt5tm2cEUCOMMWtsiGtROSA26Sortm2creERT2BrnGtROSA26SorGtROSA26SorPrmt5tm2cEUCOMMWtsiGtROSA26Sortm2creERT2Brn
• abnormal embryonic/fetal subventricular zone morphology_Prmt5<tm2c(EUCOMM)Wtsi>/Prmt5<tm2c(EUCOMM)Wtsi>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0004274B6CgPrmt5tm2cEUCOMMWtsiTgNescre1KlnPrmt5tm2cEUCOMMWtsiPrmt5tm2cEUCOMMWtsiTgNescre1Kln0TgNescre1KlnPrmt5tm2cEUCOMMWtsi
• abnormal neuronal precursor proliferation_Prmt5<tm2c(EUCOMM)Wtsi>/Prmt5<tm2c(EUCOMM)Wtsi>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0004948B6CgPrmt5tm2cEUCOMMWtsiTgNescre1KlnPrmt5tm2cEUCOMMWtsiPrmt5tm2cEUCOMMWtsiTgNescre1Kln0TgNescre1KlnPrmt5tm2cEUCOMMWtsi
• thin cerebral cortex_Prmt5<tm2c(EUCOMM)Wtsi>/Prmt5<tm2c(EUCOMM)Wtsi>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0006254B6CgPrmt5tm2cEUCOMMWtsiTgNescre1KlnPrmt5tm2cEUCOMMWtsiPrmt5tm2cEUCOMMWtsiTgNescre1Kln0TgNescre1KlnPrmt5tm2cEUCOMMWtsi
• abnormal cortical plate morphology_Prmt5<tm2c(EUCOMM)Wtsi>/Prmt5<tm2c(EUCOMM)Wtsi>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0008439B6CgPrmt5tm2cEUCOMMWtsiTgNescre1KlnPrmt5tm2cEUCOMMWtsiPrmt5tm2cEUCOMMWtsiTgNescre1Kln0TgNescre1KlnPrmt5tm2cEUCOMMWtsi
• abnormal cortical ventricular zone morphology_Prmt5<tm2c(EUCOMM)Wtsi>/Prmt5<tm2c(EUCOMM)Wtsi>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0008458B6CgPrmt5tm2cEUCOMMWtsiTgNescre1KlnPrmt5tm2cEUCOMMWtsiPrmt5tm2cEUCOMMWtsiTgNescre1Kln0TgNescre1KlnPrmt5tm2cEUCOMMWtsi
• enlarged lateral ventricles_Prmt5<tm2c(EUCOMM)Wtsi>/Prmt5<tm2c(EUCOMM)Wtsi>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0008535B6CgPrmt5tm2cEUCOMMWtsiTgNescre1KlnPrmt5tm2cEUCOMMWtsiPrmt5tm2cEUCOMMWtsiTgNescre1Kln0TgNescre1KlnPrmt5tm2cEUCOMMWtsi
• postnatal lethality, complete penetrance_Prmt5<tm2c(EUCOMM)Wtsi>/Prmt5<tm2c(EUCOMM)Wtsi>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0011085B6CgPrmt5tm2cEUCOMMWtsiTgNescre1KlnPrmt5tm2cEUCOMMWtsiPrmt5tm2cEUCOMMWtsiTgNescre1Kln0TgNescre1KlnPrmt5tm2cEUCOMMWtsi

class

http://purl.org/net/cito/citesAsAuthority

• Prmt5<tm2c(EUCOMM)Wtsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5546597