increased autoantibody level_Gt(ROSA)26Sor<tm1(Ptpn22*)Draw>/Gt(ROSA)26Sor<+>,Cd19<tm1(cre)Cgn>/Cd19<+>

http://metadb.riken.jp/0003725I129P2OlaHsdC57BL6GtROSA26Sortm1Ptpn22DrawGtROSA26SorCd19tm1creCgnCd19Cd19GtROSA26SorGtROSA26Sortm1Ptpn22DrawCd19tm1creCgn

increased autoantibody level_Gt(ROSA)26Sor<tm1(Ptpn22*)Draw>/Gt(ROSA)26Sor<+>,Cd19<tm1(cre)Cgn>/Cd19<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CD19 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88319
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(Ptpn22*)Draw>/Gt(ROSA)26Sor<+>,Cd19<tm1(cre)Cgn>/Cd19<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cd19<+>|Gt(ROSA)26Sor<+>|Gt(ROSA)26Sor<tm1(Ptpn22*)Draw>|Cd19<tm1(cre)Cgn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased autoantibody level
  http://purl.obolibrary.org/obo/MP_0003725

文献

http://purl.org/net/cito/citesAsAuthority

• Xuezhi. Dai, et.al., A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models., The Journal of clinical investigation, 2013, 123
  http://rdf.ncbi.nlm.nih.gov/pubmed/23619366