abnormal retinal photoreceptor layer morphology_Crb1<tm1Wij>/Crb1<+>,Crb2<tm1.1Wij>/Crb2<tm1.1Wij>,Tg(Chx10-EGFP/cre,-ALPP)2Clc/0

http://metadb.riken.jp/0003728I129P2OlaHsdC57BL6C57BL6JOlaHsdSJLCrb1tm1WijCrb1Crb2tm11WijCrb2tm11WijTgChx10EGFPcreALPP2Clc0TgChx10EGFPcreALPP2ClcCrb2tm11WijCrb1tm1WijCrb1

abnormal retinal photoreceptor layer morphology_Crb1<tm1Wij>/Crb1<+>,Crb2<tm1.1Wij>/Crb2<tm1.1Wij>,Tg(Chx10-EGFP/cre,-ALPP)2Clc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 2, Constance L Cepko
  http://metadb.riken.jp/db/mgi_rdf/MGI:3052233
• crumbs family member 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:2679260
• crumbs family member 1, photoreceptor morphogenesis associated
  http://metadb.riken.jp/db/mgi_rdf/MGI:2136343

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Crb1<tm1Wij>/Crb1<+>,Crb2<tm1.1Wij>/Crb2<tm1.1Wij>,Tg(Chx10-EGFP/cre,-ALPP)2Clc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Chx10-EGFP/cre,-ALPP)2Clc|Crb2<tm1.1Wij>|Crb1<tm1Wij>|Crb1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * C57BL/6JOlaHsd * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal retinal photoreceptor layer morphology
  http://purl.obolibrary.org/obo/MP_0003728

文献

http://purl.org/net/cito/citesAsAuthority

• Lucie P. Pellissier, et.al., Targeted ablation of CRB1 and CRB2 in retinal progenitor cells mimics Leber congenital amaurosis., PLoS genetics, 2013, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/24339791