abnormal facial morphology_Fgf8<tm1.4Mrt>/Fgf8<+>,Tfap2a<tm1Will>/Tfap2a<tm2.1Will>

http://metadb.riken.jp/0003743I129P2OlaHsd129S1SvBlackSwissFgf8tm14MrtFgf8Tfap2atm1WillTfap2atm21WillFgf8tm14MrtTfap2atm1WillFgf8Tfap2atm21Will

abnormal facial morphology_Fgf8<tm1.4Mrt>/Fgf8<+>,Tfap2a<tm1Will>/Tfap2a<tm2.1Will>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transcription factor AP-2, alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:104671
• fibroblast growth factor 8
  http://metadb.riken.jp/db/mgi_rdf/MGI:99604

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fgf8<tm1.4Mrt>/Fgf8<+>,Tfap2a<tm1Will>/Tfap2a<tm2.1Will>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Fgf8<tm1.4Mrt>|Tfap2a<tm1Will>|Fgf8<+>|Tfap2a<tm2.1Will>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/Sv * Black Swiss

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal facial morphology
  http://purl.obolibrary.org/obo/MP_0003743

文献

http://purl.org/net/cito/citesAsAuthority

• Rebecca M. Green, et.al., Tfap2a-dependent changes in mouse facial morphology result in clefting that can be ameliorated by a reduction in Fgf8 gene dosage., Disease models & mechanisms, 2015, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/25381013