http://rdf.ncbi.nlm.nih.gov/pubmed/25381013

http://rdf.ncbi.nlm.nih.gov/pubmed/25381013

Rebecca M. Green, et.al., Tfap2a-dependent changes in mouse facial morphology result in clefting that can be ameliorated by a reduction in Fgf8 gene dosage., Disease models & mechanisms, 2015, 8

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal nasal pit morphology_Fgf8<tm1.4Mrt>/Fgf8<+>,Tfap2a<tm1Will>/Tfap2a<tm2.1Will>
  http://metadb.riken.jp/0006306I129P2OlaHsd129S1SvBlackSwissFgf8tm14MrtFgf8Tfap2atm1WillTfap2atm21WillFgf8tm14MrtTfap2atm1WillFgf8Tfap2atm21Will
• abnormal craniofacial development_Tfap2a<tm1Will>/Tfap2a<tm2.1Will>
  http://metadb.riken.jp/0003935I129S1SvBlackSwissTfap2atm1WillTfap2atm21WillTfap2atm1WillTfap2atm21Will
• polydactyly_Tfap2a<tm1Will>/Tfap2a<tm2.1Will>
  http://metadb.riken.jp/0000562I129S1SvBlackSwissTfap2atm1WillTfap2atm21WillTfap2atm1WillTfap2atm21Will
• abnormal premaxilla morphology_Tfap2a<tm1Will>/Tfap2a<tm2.1Will>
  http://metadb.riken.jp/0002820I129S1SvBlackSwissTfap2atm1WillTfap2atm21WillTfap2atm1WillTfap2atm21Will
• cleft primary palate_Fgf8<tm1.4Mrt>/Fgf8<+>,Tfap2a<tm1Will>/Tfap2a<tm2.1Will>
  http://metadb.riken.jp/0009893I129P2OlaHsd129S1SvBlackSwissFgf8tm14MrtFgf8Tfap2atm1WillTfap2atm21WillFgf8tm14MrtTfap2atm1WillFgf8Tfap2atm21Will
• abnormal lateral nasal prominence morphology_Tfap2a<tm1Will>/Tfap2a<tm2.1Will>
  http://metadb.riken.jp/0009902I129S1SvBlackSwissTfap2atm1WillTfap2atm21WillTfap2atm1WillTfap2atm21Will
• abnormal maxillary prominence morphology_Tfap2a<tm1Will>/Tfap2a<tm2.1Will>
  http://metadb.riken.jp/0010940I129S1SvBlackSwissTfap2atm1WillTfap2atm21WillTfap2atm1WillTfap2atm21Will
• abnormal medial nasal prominence morphology_Tfap2a<tm1Will>/Tfap2a<tm2.1Will>
  http://metadb.riken.jp/0009903I129S1SvBlackSwissTfap2atm1WillTfap2atm21WillTfap2atm1WillTfap2atm21Will
• abnormal facial morphology_Fgf8<tm1.4Mrt>/Fgf8<+>,Tfap2a<tm1Will>/Tfap2a<tm2.1Will>
  http://metadb.riken.jp/0003743I129P2OlaHsd129S1SvBlackSwissFgf8tm14MrtFgf8Tfap2atm1WillTfap2atm21WillFgf8tm14MrtTfap2atm1WillFgf8Tfap2atm21Will
• facial cleft_Tfap2a<tm1Will>/Tfap2a<tm2.1Will>
  http://metadb.riken.jp/0008797I129S1SvBlackSwissTfap2atm1WillTfap2atm21WillTfap2atm1WillTfap2atm21Will
• cleft palate_Tfap2a<tm1Will>/Tfap2a<tm2.1Will>
  http://metadb.riken.jp/0000111I129S1SvBlackSwissTfap2atm1WillTfap2atm21WillTfap2atm1WillTfap2atm21Will
• abnormal secondary palate morphology_Tfap2a<tm1Will>/Tfap2a<tm2.1Will>
  http://metadb.riken.jp/0013550I129S1SvBlackSwissTfap2atm1WillTfap2atm21WillTfap2atm1WillTfap2atm21Will
• perinatal lethality_Tfap2a<tm1Will>/Tfap2a<tm2.1Will>
  http://metadb.riken.jp/0002081I129S1SvBlackSwissTfap2atm1WillTfap2atm21WillTfap2atm1WillTfap2atm21Will
• abnormal maxilla morphology_Tfap2a<tm1Will>/Tfap2a<tm2.1Will>
  http://metadb.riken.jp/0000455I129S1SvBlackSwissTfap2atm1WillTfap2atm21WillTfap2atm1WillTfap2atm21Will
• abnormal facial morphology_Tfap2a<tm1Will>/Tfap2a<tm2.1Will>
  http://metadb.riken.jp/0003743I129S1SvBlackSwissTfap2atm1WillTfap2atm21WillTfap2atm1WillTfap2atm21Will
• abnormal nasal pit morphology_Tfap2a<tm1Will>/Tfap2a<tm2.1Will>
  http://metadb.riken.jp/0006306I129S1SvBlackSwissTfap2atm1WillTfap2atm21WillTfap2atm1WillTfap2atm21Will
• abnormal neural tube closure_Tfap2a<tm1Will>/Tfap2a<tm2.1Will>
  http://metadb.riken.jp/0003720I129S1SvBlackSwissTfap2atm1WillTfap2atm21WillTfap2atm1WillTfap2atm21Will
• exencephaly_Tfap2a<tm1Will>/Tfap2a<tm2.1Will>
  http://metadb.riken.jp/0000914I129S1SvBlackSwissTfap2atm1WillTfap2atm21WillTfap2atm1WillTfap2atm21Will
• no abnormal phenotype detected_Tfap2a<tm2.1Will>/Tfap2a<tm2.1Will>
  http://metadb.riken.jp/0002169I129S1SvBlackSwissTfap2atm21WillTfap2atm21WillTfap2atm21Will