abnormal mucosal lining of the mouth_Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(KRT14-cre)8Brn/0,Tg(KRT5-Akt1*)Jmpa/0

http://metadb.riken.jp/0003745I129C57BL6DBA2DBA2JFVBNRb1tm2BrnRb1tm2BrnTgKRT14cre8Brn0TgKRT5Akt1Jmpa0TgKRT5Akt1JmpaRb1tm2BrnTgKRT14cre8Brn

abnormal mucosal lining of the mouth_Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(KRT14-cre)8Brn/0,Tg(KRT5-Akt1*)Jmpa/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• RB transcriptional corepressor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97874
• transgene insertion 8, Anton Berns
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177242
• transgene insertion, Jesus M Paramio
  http://metadb.riken.jp/db/mgi_rdf/MGI:3842825

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(KRT14-cre)8Brn/0,Tg(KRT5-Akt1*)Jmpa/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(KRT5-Akt1*)Jmpa|Rb1<tm2Brn>|Tg(KRT14-cre)8Brn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * DBA/2 * DBA/2J * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal mucosal lining of the mouth
  http://purl.obolibrary.org/obo/MP_0003745

文献

http://purl.org/net/cito/citesAsAuthority

• Marta. Moral, et.al., Akt activation synergizes with Trp53 loss in oral epithelium to produce a novel mouse model for head and neck squamous cell carcinoma., Cancer research, 2009, 69
  http://rdf.ncbi.nlm.nih.gov/pubmed/19176372