increased hepatocyte apoptosis_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0003887I129S4SvJaeC57BL6DBAPtentm1HwuPtentm1HwuTgAlbcre21Mgn0Ptentm1HwuTgAlbcre21Mgn

increased hepatocyte apoptosis_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pten<tm1Hwu>|Tg(Alb-cre)21Mgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hepatocyte apoptosis
  http://purl.obolibrary.org/obo/MP_0003887

文献

http://purl.org/net/cito/citesAsAuthority

• Vivian A. Galicia, et.al., Expansion of hepatic tumor progenitor cells in Pten-null mice requires liver injury and is reversed by loss of AKT2., Gastroenterology, 2010, 139
  http://rdf.ncbi.nlm.nih.gov/pubmed/20837017