increased hepatocyte apoptosis_Chuk<tm1Ver>/Chuk<tm1Ver>,Ikbkb<tm1Ver>/Ikbkb<tm1Ver>

http://metadb.riken.jp/0003887I129S4SvJaeC57BL6JChuktm1VerChuktm1VerIkbkbtm1VerIkbkbtm1VerChuktm1VerIkbkbtm1Ver

increased hepatocyte apoptosis_Chuk<tm1Ver>/Chuk<tm1Ver>,Ikbkb<tm1Ver>/Ikbkb<tm1Ver>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• inhibitor of kappaB kinase beta
  http://metadb.riken.jp/db/mgi_rdf/MGI:1338071
• conserved helix-loop-helix ubiquitous kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:99484

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Chuk<tm1Ver>/Chuk<tm1Ver>,Ikbkb<tm1Ver>/Ikbkb<tm1Ver>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Chuk<tm1Ver>|Ikbkb<tm1Ver>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hepatocyte apoptosis
  http://purl.obolibrary.org/obo/MP_0003887

文献

http://purl.org/net/cito/citesAsAuthority

• Q. Li, et.al., Complete lack of NF-kappaB activity in IKK1 and IKK2 double-deficient mice: additional defect in neurulation., Genes & development, 2000, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/10898787