Q. Li, et.al., Complete lack of NF-kappaB activity in IKK1 and IKK2 double-deficient mice: additional defect in neurulation., Genes & development, 2000, 14

http://rdf.ncbi.nlm.nih.gov/pubmed/10898787

Q. Li, et.al., Complete lack of NF-kappaB activity in IKK1 and IKK2 double-deficient mice: additional defect in neurulation., Genes & development, 2000, 14

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• curly tail_Chuk<tm1Ver>/Chuk<tm1Ver>,Ikbkb<tm1Ver>/Ikbkb<tm1Ver>,Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>
  http://metadb.riken.jp/0003051I129Sv129S4SvJaeC57BL6JChuktm1VerChuktm1VerIkbkbtm1VerIkbkbtm1VerTnfrsf1atm1MakTnfrsf1atm1MakIkbkbtm1VerTnfrsf1atm1MakChuktm1Ver
• abnormal hindbrain morphology_Chuk<tm1Ver>/Chuk<tm1Ver>,Ikbkb<tm1Ver>/Ikbkb<tm1Ver>
  http://metadb.riken.jp/0000841I129S4SvJaeC57BL6JChuktm1VerChuktm1VerIkbkbtm1VerIkbkbtm1VerChuktm1VerIkbkbtm1Ver
• abnormal cell physiology_Chuk<tm1Ver>/Chuk<tm1Ver>,Ikbkb<tm1Ver>/Ikbkb<tm1Ver>
  http://metadb.riken.jp/0005621I129S4SvJaeC57BL6JChuktm1VerChuktm1VerIkbkbtm1VerIkbkbtm1VerChuktm1VerIkbkbtm1Ver
• lethality throughout fetal growth and development, complete penetrance_Chuk<tm1Ver>/Chuk<tm1Ver>,Ikbkb<tm1Ver>/Ikbkb<tm1Ver>,Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>
  http://metadb.riken.jp/0011099I129Sv129S4SvJaeC57BL6JChuktm1VerChuktm1VerIkbkbtm1VerIkbkbtm1VerTnfrsf1atm1MakTnfrsf1atm1MakIkbkbtm1VerTnfrsf1atm1MakChuktm1Ver
• liver degeneration_Chuk<tm1Ver>/Chuk<tm1Ver>,Ikbkb<tm1Ver>/Ikbkb<tm1Ver>
  http://metadb.riken.jp/0003103I129S4SvJaeC57BL6JChuktm1VerChuktm1VerIkbkbtm1VerIkbkbtm1VerChuktm1VerIkbkbtm1Ver
• abnormal dorsal root ganglion morphology_Chuk<tm1Ver>/Chuk<tm1Ver>,Ikbkb<tm1Ver>/Ikbkb<tm1Ver>
  http://metadb.riken.jp/0000961I129S4SvJaeC57BL6JChuktm1VerChuktm1VerIkbkbtm1VerIkbkbtm1VerChuktm1VerIkbkbtm1Ver
• broad limb buds_Chuk<tm1Ver>/Chuk<tm1Ver>,Ikbkb<tm1Ver>/Ikbkb<tm1Ver>,Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>
  http://metadb.riken.jp/0004574I129Sv129S4SvJaeC57BL6JChuktm1VerChuktm1VerIkbkbtm1VerIkbkbtm1VerTnfrsf1atm1MakTnfrsf1atm1MakIkbkbtm1VerTnfrsf1atm1MakChuktm1Ver
• abnormal neural fold elevation formation_Chuk<tm1Ver>/Chuk<tm1Ver>,Ikbkb<tm1Ver>/Ikbkb<tm1Ver>
  http://metadb.riken.jp/0004838I129S4SvJaeC57BL6JChuktm1VerChuktm1VerIkbkbtm1VerIkbkbtm1VerChuktm1VerIkbkbtm1Ver
• curly tail_Chuk<tm1Ver>/Chuk<tm1Ver>,Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>
  http://metadb.riken.jp/0003051I129Sv129S4SvJaeC57BL6JChuktm1VerChuktm1VerTnfrsf1atm1MakTnfrsf1atm1MakChuktm1VerTnfrsf1atm1Mak
• broad limb buds_Chuk<tm1Ver>/Chuk<tm1Ver>,Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>
  http://metadb.riken.jp/0004574I129Sv129S4SvJaeC57BL6JChuktm1VerChuktm1VerTnfrsf1atm1MakTnfrsf1atm1MakChuktm1VerTnfrsf1atm1Mak
• increased embryonic neuroepithelium apoptosis_Chuk<tm1Ver>/Chuk<tm1Ver>,Ikbkb<tm1Ver>/Ikbkb<tm1Ver>
  http://metadb.riken.jp/0012701I129S4SvJaeC57BL6JChuktm1VerChuktm1VerIkbkbtm1VerIkbkbtm1VerChuktm1VerIkbkbtm1Ver
• open neural tube_Chuk<tm1Ver>/Chuk<tm1Ver>,Ikbkb<tm1Ver>/Ikbkb<tm1Ver>,Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>
  http://metadb.riken.jp/0000929I129Sv129S4SvJaeC57BL6JChuktm1VerChuktm1VerIkbkbtm1VerIkbkbtm1VerTnfrsf1atm1MakTnfrsf1atm1MakIkbkbtm1VerTnfrsf1atm1MakChuktm1Ver
• open neural tube_Chuk<tm1Ver>/Chuk<tm1Ver>,Ikbkb<tm1Ver>/Ikbkb<tm1Ver>
  http://metadb.riken.jp/0000929I129S4SvJaeC57BL6JChuktm1VerChuktm1VerIkbkbtm1VerIkbkbtm1VerChuktm1VerIkbkbtm1Ver
• embryonic lethality during organogenesis, complete penetrance_Chuk<tm1Ver>/Chuk<tm1Ver>,Ikbkb<tm1Ver>/Ikbkb<tm1Ver>
  http://metadb.riken.jp/0011098I129S4SvJaeC57BL6JChuktm1VerChuktm1VerIkbkbtm1VerIkbkbtm1VerChuktm1VerIkbkbtm1Ver
• increased hepatocyte apoptosis_Chuk<tm1Ver>/Chuk<tm1Ver>,Ikbkb<tm1Ver>/Ikbkb<tm1Ver>
  http://metadb.riken.jp/0003887I129S4SvJaeC57BL6JChuktm1VerChuktm1VerIkbkbtm1VerIkbkbtm1VerChuktm1VerIkbkbtm1Ver
• increased hindbrain apoptosis_Chuk<tm1Ver>/Chuk<tm1Ver>,Ikbkb<tm1Ver>/Ikbkb<tm1Ver>
  http://metadb.riken.jp/0012261I129S4SvJaeC57BL6JChuktm1VerChuktm1VerIkbkbtm1VerIkbkbtm1VerChuktm1VerIkbkbtm1Ver
• increased spinal cord apoptosis_Chuk<tm1Ver>/Chuk<tm1Ver>,Ikbkb<tm1Ver>/Ikbkb<tm1Ver>
  http://metadb.riken.jp/0013182I129S4SvJaeC57BL6JChuktm1VerChuktm1VerIkbkbtm1VerIkbkbtm1VerChuktm1VerIkbkbtm1Ver
• small embryonic telencephalon_Chuk<tm1Ver>/Chuk<tm1Ver>,Ikbkb<tm1Ver>/Ikbkb<tm1Ver>
  http://metadb.riken.jp/0000936I129S4SvJaeC57BL6JChuktm1VerChuktm1VerIkbkbtm1VerIkbkbtm1VerChuktm1VerIkbkbtm1Ver