increased hepatocyte apoptosis_Aldh2<tm1.1Mak>/Aldh2<tm1.1Mak>

http://metadb.riken.jp/0003887I129S6SvEvTacC57BL6JAldh2tm11MakAldh2tm11MakAldh2tm11Mak

increased hepatocyte apoptosis_Aldh2<tm1.1Mak>/Aldh2<tm1.1Mak>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• aldehyde dehydrogenase 2, mitochondrial
  http://metadb.riken.jp/db/mgi_rdf/MGI:99600

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Aldh2<tm1.1Mak>/Aldh2<tm1.1Mak>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Aldh2<tm1.1Mak>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hepatocyte apoptosis
  http://purl.obolibrary.org/obo/MP_0003887

文献

http://purl.org/net/cito/citesAsAuthority

• Shengfang. Jin, et.al., ALDH2(E487K) mutation increases protein turnover and promotes murine hepatocarcinogenesis., Proceedings of the National Academy of Sciences of the United States of America, 2015, 112
  http://rdf.ncbi.nlm.nih.gov/pubmed/26150517