increased hepatocyte proliferation_Col1a1<tm1(tetO-Tcfap2c)Hsc>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>

http://metadb.riken.jp/0003893I129S4SvJaeC57BL6Col1a1tm1tetOTcfap2cHscCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1tm1tetOTcfap2cHscGtROSA26SorCol1a1GtROSA26Sortm1rtTAM2Jae

increased hepatocyte proliferation_Col1a1<tm1(tetO-Tcfap2c)Hsc>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• collagen, type I, alpha 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88467
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Col1a1<tm1(tetO-Tcfap2c)Hsc>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Col1a1<tm1(tetO-Tcfap2c)Hsc>|Gt(ROSA)26Sor<+>|Col1a1<+>|Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hepatocyte proliferation
  http://purl.obolibrary.org/obo/MP_0003893

文献

http://purl.org/net/cito/citesAsAuthority

• Daniel. Holl, et.al., Transgenic overexpression of Tcfap2c/AP-2gamma results in liver failure and intestinal dysplasia., PloS one, 2011, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/21779369