abnormal heart right ventricle morphology_Bmp4<tm2(tetO-Bmp4,lacZ)Jfm>/?,Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/?,Tg(Mef2c-cre)2Blk/?

http://metadb.riken.jp/0003920I129S1Sv129S4SvJaeSor129X1SvJBmp4tm2tetOBmp4lacZJfmGtROSA26Sortm1rtTAEGFPNagyTgMef2ccre2BlkBmp4tm2tetOBmp4lacZJfmTgMef2ccre2BlkGtROSA26Sortm1rtTAEGFPNagy

abnormal heart right ventricle morphology_Bmp4<tm2(tetO-Bmp4,lacZ)Jfm>/?,Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/?,Tg(Mef2c-cre)2Blk/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• bone morphogenetic protein 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:88180
• transgene insertion 2, Brian L Black
  http://metadb.riken.jp/db/mgi_rdf/MGI:3639733
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bmp4<tm2(tetO-Bmp4,lacZ)Jfm>/?,Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/?,Tg(Mef2c-cre)2Blk/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Bmp4<tm2(tetO-Bmp4,lacZ)Jfm>|Tg(Mef2c-cre)2Blk|Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal heart right ventricle morphology
  http://purl.obolibrary.org/obo/MP_0003920

文献

http://purl.org/net/cito/citesAsAuthority

• Jun. Wang, et.al., Bmp signaling regulates myocardial differentiation from cardiac progenitors through a MicroRNA-mediated mechanism., Developmental cell, 2010, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/21145505