Jun. Wang, et.al., Bmp signaling regulates myocardial differentiation from cardiac progenitors through a MicroRNA-mediated mechanism., Developmental cell, 2010, 19

http://rdf.ncbi.nlm.nih.gov/pubmed/21145505

Jun. Wang, et.al., Bmp signaling regulates myocardial differentiation from cardiac progenitors through a MicroRNA-mediated mechanism., Developmental cell, 2010, 19

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Bmp4<tm2(tetO-Bmp4,lacZ)Jfm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4941211

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal cardiac outflow tract development_Bmp4<tm1Jfm>/Bmp4<tm1Jfm>,Tg(Mef2c-cre)2Blk/0
  http://metadb.riken.jp/0006126I129S4SvJaeSorBmp4tm1JfmBmp4tm1JfmTgMef2ccre2Blk0TgMef2ccre2BlkBmp4tm1Jfm
• pericardial edema_Bmp2<tm1Jfm>/Bmp2<tm1Jfm>,Bmp4<tm1Jfm>/Bmp4<tm1Jfm>,Tg(Mef2c-cre)2Blk/0
  http://metadb.riken.jp/0001787I129S4SvJaeSorBmp2tm1JfmBmp2tm1JfmBmp4tm1JfmBmp4tm1JfmTgMef2ccre2Blk0TgMef2ccre2BlkBmp2tm1JfmBmp4tm1Jfm
• embryonic lethality during organogenesis, complete penetrance_Bmp2<tm1Jfm>/Bmp2<tm1Jfm>,Bmp4<tm1Jfm>/Bmp4<tm1Jfm>,Tg(Mef2c-cre)2Blk/0
  http://metadb.riken.jp/0011098I129S4SvJaeSorBmp2tm1JfmBmp2tm1JfmBmp4tm1JfmBmp4tm1JfmTgMef2ccre2Blk0TgMef2ccre2BlkBmp2tm1JfmBmp4tm1Jfm
• abnormal heart and great artery attachment_Bmp4<tm1Jfm>/Bmp4<tm1Jfm>,Tg(Mef2c-cre)2Blk/0
  http://metadb.riken.jp/0010426I129S4SvJaeSorBmp4tm1JfmBmp4tm1JfmTgMef2ccre2Blk0TgMef2ccre2BlkBmp4tm1Jfm
• abnormal heart right ventricle morphology_Bmp4<tm2(tetO-Bmp4,lacZ)Jfm>/?,Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/?,Tg(Mef2c-cre)2Blk/?
  http://metadb.riken.jp/0003920I129S1Sv129S4SvJaeSor129X1SvJBmp4tm2tetOBmp4lacZJfmGtROSA26Sortm1rtTAEGFPNagyTgMef2ccre2BlkBmp4tm2tetOBmp4lacZJfmTgMef2ccre2BlkGtROSA26Sortm1rtTAEGFPNagy
• decreased heart right ventricle size_Mirc1<tm1.2Tyj>/Mirc1<tm1.2Tyj>
  http://metadb.riken.jp/0003649I129S4SvJaeC57BL6Mirc1tm12TyjMirc1tm12TyjMirc1tm12Tyj
• abnormal truncus arteriosus septation_Bmp4<tm1Jfm>/Bmp4<tm1Jfm>,Mirc1<tm1.2Tyj>/Mirc1<tm1.2Tyj>,Tg(Mef2c-cre)2Blk/0
  http://metadb.riken.jp/0010454I129S4SvJaeSorC57BL6Bmp4tm1JfmBmp4tm1JfmMirc1tm12TyjMirc1tm12TyjTgMef2ccre2Blk0Mirc1tm12TyjTgMef2ccre2BlkBmp4tm1Jfm
• thick myocardium_Bmp4<tm2(tetO-Bmp4,lacZ)Jfm>/?,Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/?,Tg(Mef2c-cre)2Blk/?
  http://metadb.riken.jp/0010656I129S1Sv129S4SvJaeSor129X1SvJBmp4tm2tetOBmp4lacZJfmGtROSA26Sortm1rtTAEGFPNagyTgMef2ccre2BlkBmp4tm2tetOBmp4lacZJfmTgMef2ccre2BlkGtROSA26Sortm1rtTAEGFPNagy
• abnormal truncus arteriosus septation_Bmp4<tm1Jfm>/Bmp4<tm1Jfm>,Tg(Mef2c-cre)2Blk/0
  http://metadb.riken.jp/0010454I129S4SvJaeSorBmp4tm1JfmBmp4tm1JfmTgMef2ccre2Blk0TgMef2ccre2BlkBmp4tm1Jfm
• abnormal heart ventricle outflow tract morphology_Bmp2<tm1Jfm>/Bmp2<tm1Jfm>,Bmp4<tm1Jfm>/Bmp4<tm1Jfm>,Tg(Mef2c-cre)2Blk/0
  http://metadb.riken.jp/0010224I129S4SvJaeSorBmp2tm1JfmBmp2tm1JfmBmp4tm1JfmBmp4tm1JfmTgMef2ccre2Blk0TgMef2ccre2BlkBmp2tm1JfmBmp4tm1Jfm
• abnormal cardiac outflow tract development_Bmp4<tm1Jfm>/Bmp4<tm1Jfm>,Mirc1<tm1.2Tyj>/Mirc1<tm1.2Tyj>,Tg(Mef2c-cre)2Blk/0
  http://metadb.riken.jp/0006126I129S4SvJaeSorC57BL6Bmp4tm1JfmBmp4tm1JfmMirc1tm12TyjMirc1tm12TyjTgMef2ccre2Blk0Mirc1tm12TyjTgMef2ccre2BlkBmp4tm1Jfm
• double outlet right ventricle_Mirc1<tm1.2Tyj>/Mirc1<tm1.2Tyj>
  http://metadb.riken.jp/0000284I129S4SvJaeC57BL6Mirc1tm12TyjMirc1tm12TyjMirc1tm12Tyj
• ventricular septal defect_Mirc1<tm1.2Tyj>/Mirc1<tm1.2Tyj>
  http://metadb.riken.jp/0010402I129S4SvJaeC57BL6Mirc1tm12TyjMirc1tm12TyjMirc1tm12Tyj
• abnormal heart ventricle outflow tract morphology_Bmp4<tm2(tetO-Bmp4,lacZ)Jfm>/?,Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/?,Tg(Mef2c-cre)2Blk/?
  http://metadb.riken.jp/0010224I129S1Sv129S4SvJaeSor129X1SvJBmp4tm2tetOBmp4lacZJfmGtROSA26Sortm1rtTAEGFPNagyTgMef2ccre2BlkBmp4tm2tetOBmp4lacZJfmTgMef2ccre2BlkGtROSA26Sortm1rtTAEGFPNagy

class

http://purl.org/net/cito/citesAsAuthority

• Bmp4<tm2(tetO-Bmp4,lacZ)Jfm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4941211

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD20185
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD20185
• CD19757
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD19757