abnormal pancreas development_Cdkn2a<tm2Brn>/Cdkn2a<tm2Brn>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0

http://metadb.riken.jp/0003934I129P2OlaHsd129S4SvJaeFVBNCdkn2atm2BrnCdkn2atm2BrnKrastm4TyjKrasTgPdx1cre6Tuv0TgPdx1cre6TuvKrastm4TyjKrasCdkn2atm2Brn

abnormal pancreas development_Cdkn2a<tm2Brn>/Cdkn2a<tm2Brn>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 6, David A Tuveson
  http://metadb.riken.jp/db/mgi_rdf/MGI:5437123
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm2Brn>/Cdkn2a<tm2Brn>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Pdx1-cre)6Tuv|Kras<tm4Tyj>|Kras<+>|Cdkn2a<tm2Brn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal pancreas development
  http://purl.obolibrary.org/obo/MP_0003934

文献

http://purl.org/net/cito/citesAsAuthority

• Bryan. Lo, et.al., Lkb1 regulates organogenesis and early oncogenesis along AMPK-dependent and -independent pathways., The Journal of cell biology, 2012, 199
  http://rdf.ncbi.nlm.nih.gov/pubmed/23266956