Bryan. Lo, et.al., Lkb1 regulates organogenesis and early oncogenesis along AMPK-dependent and -independent pathways., The Journal of cell biology, 2012, 199

http://rdf.ncbi.nlm.nih.gov/pubmed/23266956

Bryan. Lo, et.al., Lkb1 regulates organogenesis and early oncogenesis along AMPK-dependent and -independent pathways., The Journal of cell biology, 2012, 199

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Stk11<tm1.1Gne>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5484538

class

http://purl.org/net/cito/citesAsAuthority

• Stk11<tm1.1Gne>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5484538

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased cell proliferation_Cdkn2a<tm2Brn>/Cdkn2a<tm2Brn>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0000351I129P2OlaHsd129S4SvJaeFVBNCdkn2atm2BrnCdkn2atm2BrnKrastm4TyjKrasTgPdx1cre6Tuv0TgPdx1cre6TuvKrastm4TyjKrasCdkn2atm2Brn
• abnormal lung bud morphology_Stk11<tm1.1Gne>/Stk11<tm1.1Gne>
  http://metadb.riken.jp/0010906IC57BL6NStk11tm11GneStk11tm11GneStk11tm11Gne
• increased cell proliferation_Pdx1<tm1Egs>/Pdx1<+>,Stk11<tm1.1Gne>/Stk11<tm1.1Gne>
  http://metadb.riken.jp/0000351I129S1SvC57BL6NPdx1tm1EgsPdx1Stk11tm11GneStk11tm11GneStk11tm11GnePdx1tm1EgsPdx1
• pancreas cysts_Pdx1<tm1Egs>/Pdx1<+>,Stk11<tm1.1Gne>/Stk11<tm1.1Gne>
  http://metadb.riken.jp/0003336I129S1SvC57BL6NPdx1tm1EgsPdx1Stk11tm11GneStk11tm11GneStk11tm11GnePdx1tm1EgsPdx1
• lethality throughout fetal growth and development, complete penetrance_Stk11<tm1.1Gne>/Stk11<tm1.1Gne>
  http://metadb.riken.jp/0011099IC57BL6NStk11tm11GneStk11tm11GneStk11tm11Gne
• abnormal lung development_Stk11<tm1.1Gne>/Stk11<tm1.1Gne>
  http://metadb.riken.jp/0001176IC57BL6NStk11tm11GneStk11tm11GneStk11tm11Gne
• pancreas cysts_Kras<tm4Tyj>/Kras<+>,Stk11<tm1.1Gne>/Stk11<tm1.1Gne>
  http://metadb.riken.jp/0003336I129S4SvJaeC57BL6NKrastm4TyjKrasStk11tm11GneStk11tm11GneStk11tm11GneKrasKrastm4Tyj
• abnormal pancreas development_Cdkn2a<tm2Brn>/Cdkn2a<tm2Brn>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0003934I129P2OlaHsd129S4SvJaeFVBNCdkn2atm2BrnCdkn2atm2BrnKrastm4TyjKrasTgPdx1cre6Tuv0TgPdx1cre6TuvKrastm4TyjKrasCdkn2atm2Brn
• abnormal branching involved in lung morphogenesis_Stk11<tm1.1Gne>/Stk11<tm1.1Gne>
  http://metadb.riken.jp/0011024IC57BL6NStk11tm11GneStk11tm11GneStk11tm11Gne