tonic-clonic seizures_Scn1a<tm1.1Swl>/Scn1a<tm1.1Swl>

http://metadb.riken.jp/0003997I129S1Sv129X1SvJC57BL6JNarlScn1atm11SwlScn1atm11SwlScn1atm11Swl

tonic-clonic seizures_Scn1a<tm1.1Swl>/Scn1a<tm1.1Swl>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• sodium channel, voltage-gated, type I, alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:98246

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Scn1a<tm1.1Swl>/Scn1a<tm1.1Swl>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Scn1a<tm1.1Swl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6JNarl

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• tonic-clonic seizures
  http://purl.obolibrary.org/obo/MP_0003997

文献

http://purl.org/net/cito/citesAsAuthority

• Ming-Shian. Tsai, et.al., Functional and structural deficits of the dentate gyrus network coincide with emerging spontaneous seizures in an Scn1a mutant Dravet Syndrome model during development., Neurobiology of disease, 2015, 77
  http://rdf.ncbi.nlm.nih.gov/pubmed/25725421